Chong Nigel Ian Ming, Maniam Yogeswary, Chua Yi Chian, Tang Charmaine
Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Early Psychosis Intervention Program, Institute of Mental Health, Singapore, Singapore.
Front Psychiatry. 2021 Nov 30;12:784935. doi: 10.3389/fpsyt.2021.784935. eCollection 2021.
Early intervention in patients with first episode psychosis (FEP) can improve cognitive abilities, with both short- and long-term benefits. In this paper, we describe the implementation and review of cognitive remediation training (CRT) in an Asian FEP population. The outcomes of the training are also evaluated and discussed. This naturalistic paper describes in detail the real-life implementation and conduct of CRT in an early psychosis intervention service. One hundred and nine patients with FEP underwent a 24-session CRT programme, using Cogpack and Neuropsychological Educational Approach to Remediation. The program is evaluated with pre- and post-CRT assessment scores which included Montreal Cognitive Assessment and Brief Assessment of Cognition in Schizophrenia. The rates of improvement on these cognitive assessments were evaluated using paired -tests, with statistical significance set at ≤ 0.05. Of the 109 patients who underwent CRT, a total of 92 (84.4%) completed all 24 sessions. Paired -tests between pre- and post-CRT assessments scores revealed that participants significantly improved on majority of the measures, including verbal memory, digit sequencing, and symbol coding. As with other cognitive remediation programmes, CRT has shown to improve cognitive functioning in patients with FEP. The results support the use of CRT in an Asian context and may serve as guidance for the implementation of similar training programmes in other Asian early psychosis intervention services.
对首发精神病(FEP)患者进行早期干预可改善认知能力,具有短期和长期益处。在本文中,我们描述了认知康复训练(CRT)在亚洲FEP人群中的实施与评估情况。同时对训练结果进行了评估和讨论。 这篇写实性论文详细描述了CRT在早期精神病干预服务中的实际实施与开展情况。109例FEP患者接受了为期24节的CRT项目,采用了Cogpack和神经心理学教育康复方法。该项目通过CRT前后评估分数进行评估,评估内容包括蒙特利尔认知评估和精神分裂症认知简要评估。使用配对检验评估这些认知评估的改善率,设定统计学显著性水平为≤0.05。 在接受CRT的109例患者中,共有92例(84.4%)完成了全部24节课程。CRT前后评估分数的配对检验显示,参与者在大多数测量指标上有显著改善,包括言语记忆、数字序列和符号编码。 与其他认知康复项目一样,CRT已被证明可改善FEP患者的认知功能。研究结果支持在亚洲背景下使用CRT,并可为其他亚洲早期精神病干预服务机构实施类似训练项目提供指导。