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获得性免疫缺陷综合征:枸橼酸镓-67显像

Acquired immunodeficiency syndrome: Ga-67 citrate imaging.

作者信息

Woolfenden J M, Carrasquillo J A, Larson S M, Simmons J T, Masur H, Smith P D, Shelhamer J H, Ognibene F P

出版信息

Radiology. 1987 Feb;162(2):383-7. doi: 10.1148/radiology.162.2.3492009.

Abstract

All gallium-67 citrate scans obtained in patients with acquired immunodeficiency syndrome (AIDS) at the Clinical Center, National Institutes of Health (Bethesda, Md.) were retrospectively analyzed and correlated with the results of bronchoscopy, chest radiography, and endoscopy. There were 164 scans of 95 patients. Twenty scans were from patients with Pneumocystis carinii pneumonia; 19 were abnormal, for a sensitivity of 95%. Ga-67 uptake tended to be less in patients receiving therapy for P. carinii pneumonia. Chest radiographs were normal at least initially in three patients with abnormal scans and P. carinii pneumonia. Unusually prominent colonic activity was associated with infection in some patients. No lesions of Kaposi sarcoma showed tracer uptake. Gallium scanning is useful for detecting P. carinii pneumonia and other opportunistic infections in patients with AIDS, but it is not useful for localizing Kaposi sarcoma.

摘要

对美国国立卫生研究院临床中心(马里兰州贝塞斯达)获得性免疫缺陷综合征(AIDS)患者进行的所有枸橼酸镓-67扫描进行了回顾性分析,并与支气管镜检查、胸部X线摄影和内镜检查结果进行了关联。共对95例患者进行了164次扫描。20次扫描来自卡氏肺孢子虫肺炎患者;19次扫描结果异常,敏感性为95%。接受卡氏肺孢子虫肺炎治疗的患者镓-67摄取往往较少。在3例扫描结果异常且患有卡氏肺孢子虫肺炎的患者中,胸部X线摄影至少在最初是正常的。在一些患者中,结肠异常显著的活动与感染有关。卡波西肉瘤病灶未显示示踪剂摄取。镓扫描有助于检测AIDS患者的卡氏肺孢子虫肺炎和其他机会性感染,但对卡波西肉瘤的定位没有帮助。

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