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新型冠状病毒肺炎的流行病学特征、临床特点及转归:尼日利亚中北部阿布贾阿索科罗区医院隔离与治疗中心收治的患者

Epidemiologic Characteristics, Clinical Features and Outcomes of COVID 19: Patients Admitted at the Asokoro District Hospital Isolation and Treatment Center, Abuja, North Central Nigeria.

作者信息

Onyegbutulem H C, Dogo D, Nnabuchi C V, Aghahowa M E, Alu F E, Afiomah E U, Atanda O D, Nwankwo C G, Ani-Osheku I, Olatise O O, Abolade B O, Akerele I O, Henry-Onyegbutulem P I

机构信息

Department of Internal Medicine, College of Health Sciences Nile University of Nigeria, Abuja, Nigeria.

Department of Internal Medicine, Asokoro District Hospital, Abuja, Nigeria.

出版信息

West Afr J Med. 2021 Nov 30;Vol. 38(11):1120-1128.

Abstract

BACKGROUND

The COVID -19 pandemic spread rapidly across the globe, making a land-fall on the Nigerian geo-space in early 2020. Key presenting features were; fever, dry cough, fatigue, myalgia, headache, sore-throat, abdominal pain, diarrhea, dyspnoea amongst others, with a clinical spectrum ranging from mild through severe forms. Aside infection control and supportive care, there was no specific therapy until trials with Remdesivir. Studies have described limited epidemiological findings, presentations and outcomes of COVID patients in Nigeria and elsewhere, but not for the Federal Capital Territory, (FCT) specifically Abuja, the Nation's capital city and the second epicenter of the pandemic in Nigeria. The objective of this study therefore, was to describe the Clinical and demographic characteristics of the patients admitted at the Asokoro District Hospital (ADH), Abuja.

METHODS

Retrospective study that used records of patients admitted, between April and September 2020. Data include; Socio-demographics, medical history, exposure, residential area, co-morbidities, symptoms, signs, treatment measures, duration of hospital stay and outcomes.

RESULTS

270 patients were enrolled for this study. 170(63%) males and 100(37%) females. Mean age was 40.03+13.5years. Forty-one(15.2%) had travel history while 99(36.7%) had contact with confirmed cases. Majority of the patients were married(63.33%), and had tertiary education(74.82%). Commonest symptoms were cough(43.33%), fever(36.67%), headaches(32.22%) and fatigue(31.48%). The duration of stay at the ADH ranged from 2 hours to 28 days.

CONCLUSION

Our patients were young, mainly of the upper class, educated people with mild to severe disease. There was one death, a case with multiple comorbid factors.

摘要

背景

2019冠状病毒病疫情在全球迅速蔓延,于2020年初登陆尼日利亚地区。主要临床表现包括发热、干咳、乏力、肌痛、头痛、咽痛、腹痛、腹泻、呼吸困难等,临床症状从轻症到重症不等。除了感染控制和支持治疗外,在瑞德西韦试验之前没有特效疗法。研究描述了尼日利亚及其他地区新冠患者有限的流行病学发现、临床表现和结局,但未针对联邦首都地区,特别是首都阿布贾,即尼日利亚疫情的第二个中心。因此,本研究的目的是描述在阿布贾阿索科罗区医院(ADH)住院患者的临床和人口统计学特征。

方法

采用回顾性研究,使用2020年4月至9月期间住院患者的记录。数据包括社会人口统计学、病史、暴露情况、居住地区、合并症、症状、体征、治疗措施、住院时间和结局。

结果

本研究纳入270例患者。男性170例(63%),女性100例(37%)。平均年龄为40.03±13.5岁。41例(15.2%)有旅行史,99例(36.7%)有与确诊病例接触史。大多数患者已婚(63.33%),接受过高等教育(74.82%)。最常见的症状是咳嗽(43.33%)、发热(36.67%)、头痛(32.22%)和乏力(31.48%)。在阿索科罗区医院的住院时间从2小时到28天不等。

结论

我们的患者较为年轻,主要是上层阶级、受过教育的人群,患有轻至重度疾病。有1例死亡,该病例有多种合并因素。

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