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尼日利亚拉各斯检测中心观察到的 2019 年冠状病毒病的流行情况和临床特征。

Prevalence and Clinical Characteristics of Coronavirus Disease 2019 Seen at a Testing Centre in Lagos Nigeria.

机构信息

Clinical Sciences Department, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.

Centre for Human Virology and Genomics, Nigerian Institute of Medical Research, Yaba, Lagos State, Nigeria.

出版信息

West Afr J Med. 2021 Jan;38(1):54-58.

Abstract

BACKGROUND

The SARS-CoV-2 infection continues to ravage the global community since it was declared a pandemic. The socio-demographic and clinical characteristics defining the disease are mainly from Europe and Asia. The disease symptomatology is similar to the prevalent diseases in our environment, this could result in the delay in prompt identification and appropriate management of suspected cases toward combating community transmission. This study evaluates the prevalence, socio-demographic and clinical characteristics of positive cases of COVID -19.

METHODS

This was a retrospective cohort study. Data on the socio-demographic, clinical characteristics and the results of the SARS-CoV-2 test of participants at the Nigerian Institute of Medical Research [NIMR] Modified Drive-through Centre for COVID-19 test sample collection over two months [24th February 2020- 27th April 2020] were retrieved from the electronic medical records (EMR). Data obtained were analyzed using SPSS version 22.0.

RESULTS

A total number of 481 clients were evaluated in this review. The prevalence of SARS-CoV-2 infection in the population was 14.6%. The mean age of the positive cases was 42.2 [±15.9] years. The common symptoms reported by the positive cases were fever (40.0%), cough (32.9%), sore throat (17.1%) and running nose (15.7%). Fever depicted statistical significance with positive cases with the majority being of mild to moderate clinical severity.

CONCLUSION

The prevalence of SARS-CoV-2 infection among this cohort was 14.6% with a male preponderance. Fever and sore throat were the variables that predicted SARS CoV-2 infection among our cohort.

摘要

背景

自宣布大流行以来,SARS-CoV-2 感染继续肆虐全球。定义该疾病的社会人口学和临床特征主要来自欧洲和亚洲。该疾病的症状与我们环境中的常见疾病相似,这可能导致对疑似病例的及时识别和适当管理延迟,从而难以控制社区传播。本研究评估了 COVID-19 阳性病例的流行率、社会人口学和临床特征。

方法

这是一项回顾性队列研究。从尼日利亚医学研究所[NIMR]改良的驾车通过式 COVID-19 检测样本采集中心的电子病历(EMR)中检索了在两个月内(2020 年 2 月 24 日至 2020 年 4 月 27 日)参加者的社会人口学、临床特征和 SARS-CoV-2 检测结果的数据。使用 SPSS 版本 22.0 分析获得的数据。

结果

在本次审查中,共评估了 481 名患者。人群中 SARS-CoV-2 感染的患病率为 14.6%。阳性病例的平均年龄为 42.2[±15.9]岁。阳性病例报告的常见症状有发热(40.0%)、咳嗽(32.9%)、喉咙痛(17.1%)和流鼻涕(15.7%)。发热与阳性病例具有统计学意义,大多数为轻度至中度临床严重程度。

结论

在本队列中,SARS-CoV-2 感染的患病率为 14.6%,男性居多。发热和喉咙痛是预测本队列中 SARS-CoV-2 感染的变量。

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