Department of Zoology, The University of British Columbia, Vancouver, BC, Canada.
Department of Zoology, The University of British Columbia, Vancouver, BC, Canada.
Trends Biochem Sci. 2022 Apr;47(4):284-286. doi: 10.1016/j.tibs.2021.12.003. Epub 2021 Dec 15.
In a landmark paper, del Mármol et al. describe cryo-electron microscopy (cryo-EM) structures of an insect olfactory receptor (OR) ion channel, detailing the mechanism by which odorants can directly gate ion flow and providing insights into how this incredibly diverse family of receptors have evolved to support insects navigating complex olfactory landscapes.
在一篇具有里程碑意义的论文中,del Mármol 等人描述了昆虫嗅觉受体(OR)离子通道的冷冻电子显微镜(cryo-EM)结构,详细说明了气味如何直接控制离子流动的机制,并深入了解了这个令人难以置信的多样化受体家族是如何进化以支持昆虫在复杂的嗅觉环境中导航的。