Huang Yung-Chieh, Huang Fang-Liang, Tsai Shang-Feng, Jan Sheng-Ling, Fu Lin-Shien
Division of Nephrology, Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan; School of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Division of Hematology and Oncology, Department of Pediatrics, Taichung Veterans General Hospital, Taichung, Taiwan; Hung Kuang University, Taichung, Taiwan; Institute of Biomedical Sciences, MacKay Medical College, New Taipei City, Taiwan.
Clin Biochem. 2022 Mar;101:5-8. doi: 10.1016/j.clinbiochem.2021.12.006. Epub 2021 Dec 16.
Tumor lysis syndrome (TLS) is a life-threatening condition that may occur in patients with lymphoma, leukemia, or cancers with high cellular burdens. Without appropriate treatment, electrolyte imbalances, namely hyperkalemia, hyperphosphatemia, and hypocalcemia, can be fatal in patients with TLS. In pseudohyperkalemia, concurrent hyperphosphatemia and hypocalcemia can render devising a treatment strategy challenging. We report an adolescent with T-lymphoblastic lymphoma who presented with pseudohyperkalemia but actual hyperphosphatemia and hypocalcemia, to highlight the importance of accurate clinical interpretations of laboratory data in patients with TLS.
肿瘤溶解综合征（TLS）是一种可能发生在淋巴瘤、白血病或细胞负荷高的癌症患者中的危及生命的病症。如果没有适当的治疗，电解质失衡，即高钾血症、高磷血症和低钙血症，在TLS患者中可能是致命的。在假性高钾血症中，并发的高磷血症和低钙血症会使制定治疗策略具有挑战性。我们报告了一名患有T淋巴细胞母细胞淋巴瘤的青少年，他表现为假性高钾血症，但实际存在高磷血症和低钙血症，以强调在TLS患者中准确临床解读实验室数据的重要性。
