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苏里南共和国的疾病分布——一项使用2017年国家健康基金会索赔数据库的药物流行病学分析。

The distribution of disease in the Republic of Suriname - A pharmacoepidemiological analysis using the claims database of the State Health Foundation of the year 2017.

作者信息

Sewberath Misser Vinoj H, Shankar Arti, Hindori-Mohangoo Ashna, Wickliffe Jeffrey, Lichtveld Maureen, Mans Dennis R A

机构信息

Department of Pharmacology, Faculty of Medical Sciences, Anton de Kom University of Suriname, Paramaribo, Suriname.

Tulane University School of Public Health and Tropical Medicine, New Orleans (LA), USA.

出版信息

J Public Health Epidemiol. 2021 Oct;13(4):272-281. Epub 2021 Nov 30.

PMID:34925950
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8682966/
Abstract

The patterns of prescription drug use in Suriname in the year 2017 have been determined with the purpose of obtaining indications about the distribution of disease in the country. The claims database of the State Health Foundation (Staatsziekenfonds, SZF) of Suriname was used for calculations of prescription rates of the fifty most prescribed drugs overall and after stratification according to gender, age, and residence of the insured persons. Information in the database had been de-identified, and the prescribed medicines had been coded according to the Anatomic Therapeutic Chemical Classification System. Statistically significant differences among the prescription rates were assessed with the two samples test of proportions using normal theory method and χ Goodness of Fit tests (p < 0.05). Additionally, the Bonferroni adjustment was used to adjust for type 1 error inflation resulting from multiple comparisons. Overall, drugs for the cardiovascular, respiratory, and musculo-skeletal systems had the highest prescription rates (p < 0.001). Furthermore, rates were generally higher in females than in males, in the older age groups than in younger individuals, and in the coastal regions compared to the country's interior (p < 0.001). These findings are largely in line with data found in the literature and support the use of this pharmacoepidemiological approach to assess the distribution of disease in Suriname.

摘要

为了获取有关苏里南疾病分布的线索,已确定了2017年苏里南的处方药使用模式。苏里南国家健康基金会(Staatsziekenfonds,SZF)的理赔数据库被用于计算总体上以及按被保险人的性别、年龄和居住地分层后最常处方的五十种药物的处方率。数据库中的信息已进行去识别处理,并且所开处方的药物已根据解剖治疗化学分类系统进行编码。使用正态理论方法的两样本比例检验和χ拟合优度检验(p < 0.05)评估处方率之间的统计学显著差异。此外,采用Bonferroni校正来调整因多重比较导致的I型错误膨胀。总体而言,心血管、呼吸和肌肉骨骼系统药物的处方率最高(p < 0.001)。此外,女性的处方率通常高于男性,老年组高于年轻个体,沿海地区高于该国的内陆地区(p < 0.001)。这些发现与文献中的数据基本一致,并支持使用这种药物流行病学方法来评估苏里南的疾病分布。