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[儿童和青少年甲状腺癌的细胞免疫学研究]

[Cellular immunologic studies in pediatric and juvenile thyroid cancer].

作者信息

Boros P, Csáky G, Balázs G, Szegedi G

出版信息

Zentralbl Chir. 1986;111(19):1179-82.

PMID:3492839
Abstract

Reported in this paper are findings recorded from nine thyroid cancer patients in childhood and adolescence. T-cell sub-populations were determined by means of the rosette method and by reference to monoclonal antibodies. The investigations were concerned also with detectability of tumour antigens and with cytotoxicity. The immune activity exhibited by young patients was better than that recordable from adults. These findings are likely to suggest relative benignity of thyroid cancer, when surgically treated in childhood and adolescence.

摘要

本文报告了9例儿童和青少年甲状腺癌患者的研究结果。通过玫瑰花结法并参考单克隆抗体来确定T细胞亚群。研究还涉及肿瘤抗原的可检测性和细胞毒性。年轻患者表现出的免疫活性优于成年人。这些发现可能表明,儿童和青少年期接受手术治疗的甲状腺癌相对良性。

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