Khristoforov V S, Persanov V M, Sukhomudrenko A G, Abramov V M, Zav'ialov V P
Biofizika. 1987 Jan-Feb;32(1):32-6.
A high degree of correlation between the capability of subclasses of human immunoglobulins G to form aggregates due to thermal treatment, and their complement-binding activity was established. On the basis of the experimental data obtained by the methods of light scattering, circular dichroism, microcalorimetry, it was supposed that "hinge" region of immunoglobulins G participates in the initial stage of thermal aggregation and in the activation of the process of complement binding.
