Kitamura Koichi, Hayashi Koichi, Fujitani Shigeki, Murugan Raghavan, Suzuki Toshihiko
Department of Nephrology, Endocrinology and Diabetes, Tokyo Bay Urayasu Ichikawa Medical Center, 3-4-32 Todaijima, Urayasu, Chiba, 279-0001, Japan.
Department of Emergency and Critical Care Medicine, St. Marianna University School of Medicine, Kanagawa, Japan.
J Intensive Care. 2021 Dec 20;9(1):77. doi: 10.1186/s40560-021-00590-4.
A recent worldwide survey indicates an international diversity in net ultrafiltration (UF) practices for the treatment of fluid overload in critically ill patients with acute kidney injury (AKI) requiring renal replacement therapy (RRT). The sub-analysis of the survey has demonstrated that maximum doses of furosemide used before determination of diuretic resistance are lower in Japan than those prescribed worldwide and UF is lower but is initiated earlier. In contrast, the interval during which practitioners evaluate fluid balance is longer. The characterization of RRT in critically ill patients in Japan should unveil more appropriate approaches to the successful treatment of AKI.
最近一项全球调查表明，在需要肾脏替代治疗（RRT）的急性肾损伤（AKI）重症患者中，用于治疗液体超负荷的净超滤（UF）实践存在国际差异。该调查的子分析表明，在日本，确定利尿剂抵抗之前使用的速尿最大剂量低于全球规定剂量，超滤量较低但开始较早。相比之下，从业者评估液体平衡的间隔时间更长。对日本重症患者RRT特征的描述应揭示出更适合成功治疗AKI的方法。
