Department of Bariatric Surgery and Bariatric Medicine, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
Department of Surgery, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar; College of Medicine, Qatar University, Doha, Qatar; Weill Cornell Medicine-Qatar, Doha, Qatar; School of Health and Education, University of Skovde, Skovde, Sweden.
Surg Obes Relat Dis. 2022 Mar;18(3):413-424. doi: 10.1016/j.soard.2021.10.024. Epub 2021 Nov 11.
Nutritional deficiencies among adolescents undergoing bariatric surgery (BS) have not been evaluated a in relation to patient's sex.
We compared the preoperative nutritional profile of adolescents characterized by sex and single versus multiple deficiencies.
University hospital.
Cross-sectional retrospective chart review of 415 eligible adolescents who underwent primary BS between 2011 and 2020. Data included preoperative demographic, anthropometric information as well as three sets of nutritional variables: anemia-related, calcium-related, and other nutritional variables.
The sample comprised 247 males (59.5%) with a mean age of 15.89 ± 1.03 years and a mean body mass index (BMI) of 47.80 ± 6.57 kg/m. Most common deficiencies were vitamin D (92.3%), albumin (51.8%), anemia (15.9%), zinc (11.1%), and vitamin B (8%); 21.7% had hyperparathyroidism. Females exhibited a significantly higher prevalence of low hemoglobin, low hematocrit, and iron deficiency. Multiple deficiencies were present among 97.6%, 73.2%, 23.6%, 15%, and 12.6% of adolescents, who had vitamin D, albumin, hemoglobin, zinc, and vitamin B deficiencies, respectively. Univariate analysis revealed that adolescents with a BMI of ≥50 kg/m were 1.24 times more likely to have multiple deficiencies (P = .004). Using multivariate log-binomial regression, BMI of ≥50 kg/m was a significant predictor of multiple nutritional deficiencies (P = .005, adjusted risk ratio = 1.23, 95% CI 1.06-1.42). Age and sex were not independent predictors of multiple nutritional deficiencies.
To our knowledge, this study is the first to appraise single and multiple nutritional deficiencies in adolescents undergoing BS by sex. Multiple deficiencies were common. Females are at higher risk of anemia-related deficiencies. A BMI of ≥50 kg/m independently and significantly predicted multiple nutritional deficiencies. Correction before and monitoring after surgery are important.
接受减肥手术（BS）的青少年的营养缺乏症尚未根据患者的性别进行评估。
我们比较了通过性别和单一与多种缺乏来描述的青少年的术前营养状况。
大学医院。
对 2011 年至 2020 年间接受初次 BS 的 415 名合格青少年进行了横断面回顾性图表审查。数据包括术前人口统计学，人体测量学信息以及三组营养变量：与贫血相关的，与钙相关的和其他营养变量。
该样本包括 247 名男性（59.5％），平均年龄为 15.89 ± 1.03 岁，平均体重指数（BMI）为 47.80 ± 6.57 kg/m。最常见的缺乏症是维生素 D（92.3％），白蛋白（51.8％），贫血（15.9％），锌（11.1％）和维生素 B（8％）；21.7％患有甲状旁腺功能亢进症。女性的血红蛋白，血细胞比容和缺铁症的发生率明显较高。分别有 97.6％，73.2％，23.6％，15％和 12.6％的青少年存在多种维生素 D，白蛋白，血红蛋白，锌和维生素 B 缺乏症。单变量分析显示，BMI≥50 kg/m 的青少年发生多种缺乏症的可能性高 1.24 倍（P =.004）。使用多变量对数二项式回归，BMI≥50 kg/m 是多种营养缺乏症的重要预测指标（P =.005，调整后的风险比= 1.23，95％CI 1.06-1.42）。年龄和性别不是多种营养缺乏症的独立预测因素。
据我们所知，这项研究首次按性别评估了接受 BS 的青少年的单一和多种营养缺乏症。多种缺乏症很常见。女性更容易出现与贫血相关的缺乏症。BMI≥50 kg/m 独立且显着预测多种营养缺乏症。手术前的纠正和手术后的监测很重要。
