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Antimicrobial Stewardship in the Emergency Department.急诊科的抗菌药物管理
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Factors influencing physicians' antimicrobial prescribing decisions: A systematic review of qualitative studies.影响医生抗菌药物处方决策的因素:定性研究的系统评价
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Why Do Physicians Prescribe Antibiotics? A Systematic Review of the Psycho-Socio-Organisational Factors Related to Potentially Inappropriate Prescribing of Antimicrobials in Europe.医生为何开具抗生素?对欧洲与抗菌药物潜在不适当处方相关的心理-社会-组织因素的系统评价
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1
Improving paediatric antimicrobial stewardship in hospital-based settings: why, where and how?改善医院环境下的儿科抗菌药物管理:为何、何处以及如何进行?
JAC Antimicrob Resist. 2020 Mar 13;2(1):dlaa011. doi: 10.1093/jacamr/dlaa011. eCollection 2020 Mar.
2
Using antibiotics wisely for respiratory tract infection in the era of covid-19.在新冠疫情时代合理使用抗生素治疗呼吸道感染
BMJ. 2020 Nov 13;371:m4125. doi: 10.1136/bmj.m4125.
3
Bacterial and Fungal Coinfection in Individuals With Coronavirus: A Rapid Review To Support COVID-19 Antimicrobial Prescribing.细菌和真菌合并感染冠状病毒的个体:一项支持 COVID-19 抗菌药物处方的快速综述。
Clin Infect Dis. 2020 Dec 3;71(9):2459-2468. doi: 10.1093/cid/ciaa530.
4
Optimizing design of research to evaluate antibiotic stewardship interventions: consensus recommendations of a multinational working group.优化抗生素管理干预措施研究的设计:一个跨国工作组的共识建议。
Clin Microbiol Infect. 2020 Jan;26(1):41-50. doi: 10.1016/j.cmi.2019.08.017. Epub 2019 Sep 4.
5
Knowing antmicrobial resistance in practice: a multi-country qualitative study with human and animal healthcare professionals.了解实践中的抗微生物药物耐药性:一项多国定性研究,涉及人类和动物保健专业人员。
Glob Health Action. 2019;12(1):1599560. doi: 10.1080/16549716.2019.1599560.
6
Critical Importance of a One Health Approach to Antimicrobial Resistance.“同一健康”方法对抗菌素耐药性的至关重要性。
Ecohealth. 2019 Sep;16(3):404-409. doi: 10.1007/s10393-019-01415-5. Epub 2019 Jun 28.
7
Antibiotic Prescribing During Pediatric Direct-to-Consumer Telemedicine Visits.儿科直接面向消费者的远程医疗就诊期间的抗生素处方。
Pediatrics. 2019 May;143(5). doi: 10.1542/peds.2018-2491. Epub 2019 Apr 8.
8
Investigating the cultural and contextual determinants of antimicrobial stewardship programmes across low-, middle- and high-income countries-A qualitative study.调查低、中、高收入国家抗菌药物管理计划的文化和背景决定因素——一项定性研究。
PLoS One. 2019 Jan 16;14(1):e0209847. doi: 10.1371/journal.pone.0209847. eCollection 2019.
9
Factors Influencing Prescribing Decisions of Physicians: A Review.影响医生处方决策的因素:综述
Ethiop J Health Sci. 2018 Nov;28(6):795-804. doi: 10.4314/ejhs.v28i6.15.
10
The quality of studies evaluating antimicrobial stewardship interventions: a systematic review.评价抗菌药物管理干预措施的研究质量:系统评价。
Clin Microbiol Infect. 2019 May;25(5):555-561. doi: 10.1016/j.cmi.2018.11.002. Epub 2018 Nov 23.

理解英国医生在儿童有呼吸道症状时于急诊处开抗生素处方的决策:一项定性研究。

Understanding doctors' emergency department antibiotic prescribing decisions in children with respiratory symptoms in the UK: a qualitative study.

机构信息

Faculty of Health and Life Sciences, University of Liverpool, Liverpool, UK

Alder Hey Children's NHS Foundation Trust, Liverpool, UK.

出版信息

BMJ Open. 2021 Dec 20;11(12):e051561. doi: 10.1136/bmjopen-2021-051561.

DOI:10.1136/bmjopen-2021-051561
PMID:34930732
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8688728/
Abstract

OBJECTIVE

Exploration of the factors that influence hospital doctors' antibiotic prescribing decisions when treating children with respiratory symptoms in UK emergency departments.

METHODS

A qualitative study using semistructured interviews based on a critical incident technique with 21 physicians of different grades and specialties that treat children in the UK. Interviews were audio-recorded then transcribed verbatim and analysed using thematic analysis.

RESULTS

Four themes were identified. These themes illustrate factors which influence clinician prescribing. The three principal themes were authorities, pressures and risk. The fourth transcending theme that ran through all themes was clinician awareness and complicity ('knowing but still doing').

CONCLUSIONS

Hospital doctors prescribe antibiotics even when they know they should not. This appears to be due to the influence of those in charge or external pressures experienced while weighing up the immediate and longer term risks but clinicians do this with full insight into their actions. These findings have implications for invested parties seeking to develop future antimicrobial stewardship programmes. It is recommended that stewardship interventions acknowledge and target these themes which may in turn facilitate behaviour change and antimicrobial prescribing practice in emergency departments.

摘要

目的

探索影响英国急诊科医生治疗呼吸系统症状儿童时开具抗生素处方决策的因素。

方法

采用基于关键事件技术的定性研究,对 21 名不同级别和专业的英国儿科医生进行半结构式访谈。访谈进行录音,然后逐字转录,并使用主题分析进行分析。

结果

确定了四个主题。这些主题说明了影响临床医生处方的因素。三个主要主题是权威、压力和风险。贯穿所有主题的第四个主题是临床医生的意识和共谋(“明知故犯”)。

结论

医院医生即使知道不应该开抗生素,也会开抗生素。这似乎是由于负责人的影响或在权衡短期和长期风险时所经历的外部压力所致,但临床医生对自己的行为有充分的了解。这些发现对寻求制定未来抗菌药物管理计划的相关方具有重要意义。建议管理干预措施承认和针对这些主题,这反过来可能有助于改变行为和急诊部门的抗生素处方实践。