An autoreactive T cell clone derived after allostimulation in vitro: evidence for recognition of a polymorphic self major histocompatibility complex class II gene product.
作者信息
Martin A, Eiermann T H, Tricas L, Goldmann S F
出版信息
Transplant Proc. 1987 Feb;19(1 Pt 1):875-7.
PMID:3493567
Abstract
摘要
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The regulation of expression of histocompatibility antigens on the cell surface; molecular genetic basis.细胞表面组织相容性抗原表达的调控；分子遗传学基础。
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[The major histocompatibility complex of humans].
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A novel HLA class II-independent TCR-mediated T cell activation mechanism is distinguished by the V beta specificity of the proliferating oligoclones and their capacity to generate interleukin-2.一种新型的不依赖HLA II类分子的TCR介导的T细胞激活机制，其特征在于增殖性寡克隆的Vβ特异性及其产生白细胞介素-2的能力。
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引用本文的文献
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DY determinants, possibly associated with novel class II molecules, stimulate autoreactive CD4+ T cells with suppressive activity.DY决定簇可能与新型II类分子相关，可刺激具有抑制活性的自身反应性CD4+ T细胞。
J Exp Med. 1988 Feb 1;167(2):243-61. doi: 10.1084/jem.167.2.243.
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