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接受抗逆转录病毒疗法的 HIV 感染老年人群的营养评估。

Nutritional assessment in the HIV-infected older population receiving antiretroviral therapy.

机构信息

Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences; Center of Excellence in Burn and Wound Care. Chulalongkorn University, Bangkok, Thailand.

Department of Food and Pharmaceutical Chemistry, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand.

出版信息

AIDS Rev. 2021 Dec 22;24(4):153-161. doi: 10.24875/AIDSRev.21000051.

Abstract

Malnutrition is a pronounced public health issue which often seems underestimated in the older people living with HIV (PLWH) virus infection. PLWH are highly vulnerable to nutritional problems resulting from agingrelated deterioration, disease itself, and adverse effects of antiretroviral therapy (ART). The comprehensive nutritional assessments are necessary to perform routinely in this population to monitor and provide appropriate interventions to reduce comorbid conditions. In this review, we focus on the untoward impacts of malnutrition and nutritional assessments on the morbidity and mortality in the older PLWH. Some predictive factors of nutritional status in this group of patients are discussed. We propose the important components for nutrition assessment tool for older PLWH on ART. Highlighted issue is the need for developing uniform standardized tools for the early diagnosis of malnutrition in this population. Applications of the nutritional assessments, proper nutritional interventions, and regular monitoring of nutritional status in older PLWH liv-ing in every clinical setting may help the patients get better well-being.

摘要

营养不良是一个显著的公共卫生问题,在感染 HIV 的老年人(PLWH)中似乎经常被低估。PLWH 极易受到与衰老相关的恶化、疾病本身以及抗逆转录病毒疗法(ART)的不良反应导致的营养问题的影响。为了监测和提供适当的干预措施以减少合并症,有必要对这一人群进行常规的综合营养评估。在这篇综述中,我们重点关注营养不良和营养评估对老年 PLWH 发病率和死亡率的不利影响。讨论了该组患者营养状况的一些预测因素。我们提出了针对接受 ART 的老年 PLWH 的营养评估工具的重要组成部分。突出的问题是需要为该人群开发用于早期诊断营养不良的统一标准化工具。在每个临床环境中对老年 PLWH 进行营养评估、适当的营养干预和定期监测营养状况,可能有助于改善患者的健康状况。

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