Division of Diagnostic Imaging, Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Semin Musculoskelet Radiol. 2021 Dec;25(6):795-804. doi: 10.1055/s-0041-1740351. Epub 2021 Dec 22.
Percutaneous radiofrequency ablation (RFA) is an integral component of the multidisciplinary treatment algorithm for both local tumor control and palliation of painful spine metastases. This minimally invasive therapy complements additional treatment strategies, such as pain medications, systemic chemotherapy, surgical resection, and radiotherapy. The location and size of the metastatic lesion dictate preprocedure planning and the technical approach. For example, ablation of lesions along the spinal canal, within the posterior vertebral elements, or with paraspinal soft tissue extension are associated with a higher risk of injury to adjacent spinal nerves. Additional interventions may be indicated in conjunction with RFA. For example, ablation of vertebral body lesions can precipitate new, or exacerbate existing, pathologic vertebral compression fractures that can be prevented with vertebral augmentation. This article reviews the indications, clinical work-up, and technical approach for RFA of spine metastases.
经皮射频消融(RFA)是局部肿瘤控制和缓解疼痛性脊柱转移瘤的多学科治疗方案的组成部分。这种微创治疗方法补充了其他治疗策略,如止痛药物、全身化疗、手术切除和放疗。转移瘤的位置和大小决定了术前规划和技术方法。例如,椎管内、椎骨后元素内或椎旁软组织延伸的消融与邻近脊神经损伤的风险较高相关。可能需要与 RFA 一起进行其他干预。例如,椎体病变的消融可能会引发新的或加重现有的病理性椎体压缩骨折,椎体增强可预防这种骨折。本文回顾了脊柱转移瘤 RFA 的适应证、临床评估和技术方法。