Pediatric Surgery Department, La Paz University Hospital, Madrid, Spain.
Children's Anesthesia and Resuscitation Department, La Paz University Hospital, Madrid, Spain.
Eur J Pediatr Surg. 2022 Feb;32(1):73-79. doi: 10.1055/s-0041-1740555. Epub 2021 Dec 23.
In recent years, pain protocols for pectus excavatum (PE) have incorporated cryoanalgesia through thoracoscopic approach. Since 2019, ultrasound-guided percutaneous cryoanalgesia (PCr) has been applied at our institution, either on the same day as the Nuss procedure or 48 hours before surgery. We carried out a preliminary retrospective review of patients with PE in whom PCr prior to surgery was performed at our institution between 2019 and 2021.
Two groups were evaluated: PCr on the same day (PCrSD) and PCr 48 hours before surgery (PCr48). Despite PCr, patients were treated with "patient-controlled analgesia" (PCA) with opioids for at least 24 hours, switching to conventional intravenous analgesia and oral analgesia in the following days. Demographic, clinical-radiological variables, PCA opioid use, pain grade according to the visual analog scale (VAS), and length of stay (LOS) were compared between the groups. A total of 20 patients were included (12 with PCrSD and 8 with PCr48), without significant differences in demographics or clinical-radiological variables. The overall median time of PCr was 65 minutes (55-127), with no differences between the groups.
PCr48 group presented with significantly lower median number of hours of continuous PCA (24 vs. 32 hours; = 0.031), lower median number of rescue boluses (11 vs. 18; = 0.042), lower median VAS in the early postoperative hours (2 vs. 5.5; = 0.043), and lower median LOS (3.5 vs. 5 days).
PCr performed 48 hours prior to surgery is more effective in terms of PCA requirements, VAS, and LOS when compared with cryoanalgesia on the same day.
近年来,鸡胸(pectus excavatum,PE)的疼痛方案已纳入胸腔镜下的冷冻镇痛。自 2019 年以来,我们机构已应用超声引导下经皮冷冻镇痛(PCr),可在同一天行 Nuss 手术时或术前 48 小时进行。我们对 2019 年至 2021 年期间在我们机构行术前 PCr 的 PE 患者进行了初步回顾性研究。
评估了两组患者:同一天行 PCr(PCrSD)和术前 48 小时行 PCr(PCr48)。尽管行 PCr,但所有患者均接受至少 24 小时的“患者自控镇痛(PCA)”治疗,静脉阿片类药物镇痛,并在随后几天内转换为常规静脉内镇痛和口服镇痛。比较两组患者的人口统计学、临床影像学变量、PCA 阿片类药物使用、视觉模拟评分(VAS)疼痛评分和住院时间(LOS)。共纳入 20 例患者(PCrSD 组 12 例,PCr48 组 8 例),两组患者在人口统计学和临床影像学变量方面无显著差异。PCr 的总中位数时间为 65 分钟(55-127),两组间无差异。
PCr48 组的连续 PCA 中位数时间显著缩短(24 小时比 32 小时; = 0.031),需要的解救性冲击剂量中位数减少(11 次比 18 次; = 0.042),术后早期 VAS 评分中位数降低(2 分比 5.5 分; = 0.043),LOS 中位数缩短(3.5 天比 5 天)。
与同一天行冷冻镇痛相比,术前 48 小时行 PCr 在 PCA 需求、VAS 和 LOS 方面更有效。