Grant K, Rabello Y, Freeman A G, Freeman R K, Baumgardner S
Obstet Gynecol. 1978 May;51(5):636-9. doi: 10.1097/00006250-197805000-00030.
A single 2-mg dose of quinestrol was demonstrated safe and effective for controlling postpartum lactation and for alleviating breast discomfort. A double-blind comparison to Tace 72 mg every 12 hours for 2 days, and to placebo, was made in 134 patients. The single oral dose of quinestrol showed efficacy equal to the 2-day regimen of Tace. Both were superior to placebo.
已证明单剂量2毫克炔雌醚对于控制产后泌乳和缓解乳房不适是安全有效的。对134名患者进行了双盲比较,将其与每12小时服用72毫克氯地孕酮,共服用2天的情况以及与安慰剂进行比较。单剂量口服炔雌醚显示出与氯地孕酮2天疗程相当的疗效。两者均优于安慰剂。