López Valiente Sebastian, Rodríguez Alejandro M, Long Nathan M, Quintans Graciela, Miccoli Florencia E, Lacau-Mengido Isabel M, Maresca Sebastian
Estación Experimental Agropecuaria Cuenca del Salado, Instituto Nacional de Tecnología Agropecuaria, Rauch BA 7203, Argentina.
Department of Animal and Veterinary Sciences, Clemson University, Clemson, SC 29634, USA.
Animals (Basel). 2021 Nov 27;11(12):3393. doi: 10.3390/ani11123393.
This study aimed to determine the effects of age at first gestation on offspring growth performance, glucose metabolism, and IGF1 concentration. Heifers impregnated by AI from a single bull at 15 months of age (15 M, n = 20), or 27 months of age (27 M, = 20), and multiparous cows (adult, = 20) were used. Dams from all groups were managed in a single group during gestation and lactation. Gestational length was longer in the 15 M and 27 M than in adult dams ( = 0.009). Bodyweight at birth, at weaning and ADG during lactation were higher in calves from adult dams than in those from 27 M dams, and higher in calves from the latter than in 15 M calves ( < 0.001). Calves from 15 M dams had an increased head circumference/BW ratio compared to calves from 27 M dams, while calves from this latter group had an increased ratio compared to calves from adults ( = 0.005). Body mass index was greater in calves from adults than in those from 15 M and 27 M dams ( = 0.002). Milk production from 15 M and 27 M dams was similar but lower than that from adults ( = 0.03). Calves born from adult dams had greater blood glucose concentrations than those from 15 M and 27 M dams ( < 0.05). Serum IGF1 concentrations were higher in calves from adults than in calves from 15 M and 27 M dams ( = 0.01). This study showed that age at first gestation affects offspring postnatal growth performance, glucose metabolism and IGF1 concentration.
本研究旨在确定首次妊娠年龄对后代生长性能、葡萄糖代谢和胰岛素样生长因子1（IGF1）浓度的影响。选用15月龄（15M，n = 20）或27月龄（27M，n = 20）经人工授精由同一头公牛受孕的小母牛，以及经产母牛（成年，n = 20）。所有组别的母畜在妊娠和泌乳期间集中管理。15M组和27M组的妊娠期长于成年母畜（P = 0.009）。成年母畜所生犊牛出生体重、断奶体重和泌乳期平均日增重高于27M组所生犊牛，且27M组所生犊牛高于15M组所生犊牛（P < 0.001）。与27M组所生犊牛相比，15M组所生犊牛头围/体重比增加，而27M组所生犊牛与成年组所生犊牛相比该比例增加（P = 0.005）。成年组所生犊牛的体重指数高于15M组和27M组所生犊牛（P = 0.002）。15M组和27M组母畜的产奶量相似，但低于成年组（P = 0.03）。成年母畜所生犊牛的血糖浓度高于15M组和27M组所生犊牛（P < 0.05）。成年组所生犊牛血清IGF1浓度高于15M组和27M组所生犊牛（P = 0.01）。本研究表明，首次妊娠年龄影响后代出生后的生长性能、葡萄糖代谢和IGF1浓度。
