淋巴细胞表面标志物研究在不明原因淋巴细胞增多症诊断中的应用
Lymphocyte surface marker studies in the diagnosis of unexplained lymphocytosis.
作者信息
Quantz M C, Robinson J B, Sachs V, Pinkerton P H
出版信息
CMAJ. 1987 Apr 15;136(8):835-8.
Abstract
Fifty-six patients with unexplained lymphocytosis were investigated with a panel of antibodies to lymphocyte surface antigens. In 23 the distribution of cell surface markers suggested reactive lymphocytosis. The remaining 33 patients showed a distribution of cell surface markers that indicated or suggested a diagnosis of B-cell lymphoproliferative disease. Two illustrative case reports show how such studies performed early in the investigation of unexplained lymphocytosis may permit earlier diagnosis of the underlying mechanism.
摘要
对56例不明原因淋巴细胞增多症患者进行了一组淋巴细胞表面抗原抗体检测。23例患者的细胞表面标志物分布提示反应性淋巴细胞增多。其余33例患者的细胞表面标志物分布提示或支持B细胞淋巴增殖性疾病的诊断。两篇典型病例报告显示，在不明原因淋巴细胞增多症调查早期进行的此类研究如何能够更早地诊断潜在机制。
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