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海洋健康促进化合物:其表征及人类应用的最新趋势

Marine Health-Promoting Compounds: Recent Trends for Their Characterization and Human Applications.

作者信息

Quitério Eva, Soares Cristina, Ferraz Ricardo, Delerue-Matos Cristina, Grosso Clara

机构信息

Ciências Químicas e das Biomoléculas/CISA, Escola Superior de Saúde-Instituto Politécnico do Porto, Rua Doutor António Bernardino de Almeida 400, 4200-072 Porto, Portugal.

LAQV-REQUIMTE, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Rua Doutor António Bernardino de Almeida 431, 4249-015 Porto, Portugal.

出版信息

Foods. 2021 Dec 14;10(12):3100. doi: 10.3390/foods10123100.

Abstract

Seaweeds represent a rich source of biologically active compounds with several applications, especially in the food, cosmetics, and medical fields. The beneficial effects of marine compounds on health have been increasingly explored, making them an excellent choice for the design of functional foods. When studying marine compounds, several aspects must be considered: extraction, identification and quantification methods, purification steps, and processes to increase their stability. Advanced green techniques have been used to extract these valuable compounds, and chromatographic methods have been developed to identify and quantify them. However, apart from the beneficial effects of seaweeds for human health, these natural sources of bioactive compounds can also accumulate undesirable toxic elements with potential health risks. Applying purification techniques of extracts from seaweeds may mitigate the amount of excessive toxic components, ensuring healthy and safer products for commercialization. Furthermore, limitations such as stability and bioavailability problems, chemical degradation reactions during storage, and sensitivity to oxidation and photo-oxidation, need to be overcome using, for example, nanoencapsulation techniques. Here we summarize recent advances in all steps of marine products identification and purification and highlight selected human applications, including food and feed applications, cosmetic, human health, and fertilizers, among others.

摘要

海藻是具有多种用途的生物活性化合物的丰富来源,尤其是在食品、化妆品和医学领域。海洋化合物对健康的有益作用已得到越来越多的探索,使其成为功能性食品设计的绝佳选择。在研究海洋化合物时,必须考虑几个方面:提取、鉴定和定量方法、纯化步骤以及提高其稳定性的工艺。先进的绿色技术已被用于提取这些有价值的化合物,并且已开发出色谱方法来鉴定和定量它们。然而,除了海藻对人类健康的有益作用外,这些生物活性化合物的天然来源也可能积累具有潜在健康风险的不良有毒元素。应用海藻提取物的纯化技术可能会减少过量有毒成分的含量,确保商业化产品的健康和安全。此外,诸如稳定性和生物利用度问题、储存期间的化学降解反应以及对氧化和光氧化的敏感性等限制,需要使用例如纳米封装技术来克服。在这里,我们总结了海洋产品鉴定和纯化所有步骤的最新进展,并重点介绍了选定的人类应用,包括食品和饲料应用、化妆品、人类健康以及肥料等。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5695/8702156/08421e80c07d/foods-10-03100-g001.jpg

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