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新生儿 COVID-19 重症合并脑静脉血栓形成,经瑞德西韦、糖皮质激素和高免疫血浆治疗成功。

Severe COVID-19 Complicated by Cerebral Venous Thrombosis in a Newborn Successfully Treated with Remdesivir, Glucocorticoids, and Hyperimmune Plasma.

机构信息

Academic Department of Pediatrics, Bambino Gesù Children's Hospital-IRCCS, 00165 Rome, Italy.

Department of Emergency, Acceptance and General Pediatrics, Bambino Gesù Children's Hospital, IRCCS, 00165 Rome, Italy.

出版信息

Int J Environ Res Public Health. 2021 Dec 15;18(24):13201. doi: 10.3390/ijerph182413201.

Abstract

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the coronavirus disease 2019 (COVID-19) pandemic, affecting all age groups with a wide spectrum of clinical presentation ranging from asymptomatic to severe interstitial pneumonia, hyperinflammation, and death. Children and infants generally show a mild course of the disease, although infants have been observed to have a higher risk of hospitalization and severe outcomes. Here, we report the case of a preterm infant with a severe form of SARS-CoV-2 infection complicated by cerebral venous thrombosis successfully treated with steroids, hyperimmune plasma, and remdesivir.

摘要

严重急性呼吸综合征冠状病毒 2 型(SARS-CoV-2)引发 2019 年冠状病毒病(COVID-19)大流行,影响所有年龄段人群,临床表现广泛,从无症状到严重间质性肺炎、过度炎症和死亡。儿童和婴儿通常表现为疾病的轻度病程,尽管婴儿的住院和严重后果风险较高。在这里,我们报告了一例患有严重 SARS-CoV-2 感染的早产儿的病例,该病例并发脑静脉血栓形成,经类固醇、高免疫血浆和瑞德西韦治疗后成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2584/8701660/06c065d70f45/ijerph-18-13201-g001.jpg

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