Punnonen R, Salmi J, Tuimala R, Järvinen M, Pystynen P
Maturitas. 1986 Dec;8(4):291-5. doi: 10.1016/0378-5122(86)90037-x.
Calcium (Ca) metabolism, with particular reference to serum vitamin D metabolites, was investigated in 40 women with femoral neck fracture (mean age 77.1 +/- 8.6 yr). All the patients were ambulant before the fracture; eight were long-term geriatric in-patients. Serum total and ionised calcium and serum albumin levels were significantly lower, and serum parathormone (PTH) levels significantly higher in fracture patients than in controls. Both serum 25-OH-D and 1,25-(OH)2D were significantly lower in fracture patients than in controls. We concluded that vitamin D, serum PTH and calcium levels should be checked with greater frequency in patients at high risk for osteoporosis and osteomalacia before they reach the age of 70.
对40例股骨颈骨折女性患者(平均年龄77.1±8.6岁)的钙(Ca)代谢情况进行了研究,特别关注血清维生素D代谢产物。所有患者在骨折前均能行走;其中8例为长期老年住院患者。骨折患者的血清总钙、离子钙和血清白蛋白水平显著低于对照组,血清甲状旁腺激素(PTH)水平显著高于对照组。骨折患者的血清25-OH-D和1,25-(OH)2D均显著低于对照组。我们得出结论,对于骨质疏松症和骨软化症高危患者,在70岁之前应更频繁地检查维生素D、血清PTH和钙水平。