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脾脏硬化性血管样结节性转化:一例报告。

Sclerosing angiomatoid nodular transformation of the spleen: a case report.

机构信息

General Surgery Department, Nicosia General Hospital, Leukosia, Cyprus

Histopathology Department, Nicosia General Hospital, Leukosia, Cyprus.

出版信息

BMJ Case Rep. 2021 Dec 23;14(12):e246993. doi: 10.1136/bcr-2021-246993.

DOI:10.1136/bcr-2021-246993
PMID:34949583
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8704970/
Abstract

Sclerosing angiomatoid nodular transformation (SANT) of the spleen is an uncommon primary benign condition with specific histopathological characteristics. The majority of the patients are usually asymptomatic and present for treatment after an incidental finding on a routine abdominal imaging. The differential diagnosis includes other benign tumours, as well as primary malignancy or metastases of unknown origin. We report a 55-year-old woman who was presented to the surgical team of our hospital for splenectomy after the investigation of an incidental splenic lesion led to the diagnosis of SANT. The pathology report of the specimen repeated the initial diagnosis. The patient has not yet presented any complication or recurrence of the disease 8 months after the operation. From such infrequent cases, the most valuable conclusion which can be yielded is that the more the number of patients reported, the more the knowledge about the disease is broadened.

摘要

脾脏硬化性血管样结节性转化(SANT)是一种罕见的原发性良性疾病,具有特定的组织病理学特征。大多数患者通常无症状,在常规腹部影像学检查发现偶然病变后进行治疗。鉴别诊断包括其他良性肿瘤,以及来源不明的原发性恶性肿瘤或转移瘤。我们报告了 1 例 55 岁女性患者,因偶然发现的脾脏病变就诊于我院外科团队,最终诊断为 SANT 而行脾切除术。标本的病理报告重复了最初的诊断。术后 8 个月,患者尚未出现任何并发症或疾病复发。从这些罕见的病例中,最有价值的结论是,报告的患者越多,对该疾病的认识就越广泛。

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本文引用的文献

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Reappraisal of surgical decision-making in patients with splenic sclerosing angiomatoid nodular transformation: Case series and literature review.脾脏硬化性血管瘤样结节性转化患者手术决策的重新评估:病例系列及文献综述
World J Gastrointest Surg. 2021 Aug 27;13(8):848-858. doi: 10.4240/wjgs.v13.i8.848.
2
Sclerosing angiomatoid nodular transformation presenting with thrombocytopenia after laparoscopic splenectomy - Case report and systematic review of 230 patients.腹腔镜脾切除术后出现血小板减少症的硬化性血管瘤样结节性转化——病例报告及对230例患者的系统评价
Ann Med Surg (Lond). 2020 Oct 29;60:201-210. doi: 10.1016/j.amsu.2020.10.048. eCollection 2020 Dec.
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Treatment options for sclerosing angiomatoid nodular transformation of spleen.脾脏硬化性血管瘤样结节性转化的治疗选择
HPB (Oxford). 2020 Nov;22(11):1577-1582. doi: 10.1016/j.hpb.2020.01.014. Epub 2020 Feb 13.
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Sclerosing Angiomatoid Nodular Transformation of the Spleen: Lessons from a Rare Case and Review of the Literature.脾脏硬化性血管瘤样结节性转化:来自一例罕见病例的经验及文献复习
Intern Med. 2019 May 15;58(10):1433-1441. doi: 10.2169/internalmedicine.1948-18. Epub 2019 Jan 10.
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Am J Surg Pathol. 2016 Oct;40(10):1343-51. doi: 10.1097/PAS.0000000000000716.
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Clin Nucl Med. 2014 Sep;39(9):772-6. doi: 10.1097/RLU.0000000000000523.
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AJR Am J Roentgenol. 2013 Apr;200(4):W353-60. doi: 10.2214/AJR.12.9522.
9
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Pathol Int. 2009 Dec;59(12):844-50. doi: 10.1111/j.1440-1827.2009.02456.x.
10
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Virchows Arch. 2008 Sep;453(3):275-82. doi: 10.1007/s00428-008-0648-z. Epub 2008 Aug 12.