关于正常/平衡易位嵌合体的合子前起源。
On a prezygotic origin of normal/balanced translocation mosaics.
作者信息
Cantú J M, Ruiz C
出版信息
Ann Genet. 1986;29(4):221-2.
PMID:3495220
Abstract
Based on a theoretical model for the production of some structural mosaicisms, the authors propose a mechanism for the origin of normal/balanced translocation mosaics. Single strand breaks and nonhomologous hemichromatid joining are implicated and, when applied to homologous chromosomes, could explain some instances of nondisjunction independent of centromere function.
摘要
基于一些结构镶嵌现象产生的理论模型，作者提出了一种正常/平衡易位镶嵌体起源的机制。单链断裂和非同源半染色单体连接被牵涉其中，并且当应用于同源染色体时，可以解释一些与着丝粒功能无关的不分离情况。
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