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经导管主动脉瓣置换术(TAVI)能否在无心脏外科手术部门的机构进行?

Can Transcatheter Aortic Valve Implantation (TAVI) Be Performed at Institutions Without On-Site Cardiac Surgery Departments?

机构信息

Hillel Yaffe Medical Center, Technion - Israel Institute of Technology, Haifa, Israel.

Hillel Yaffe Medical Center, Technion - Israel Institute of Technology, Haifa, Israel.

出版信息

Cardiovasc Revasc Med. 2022 Aug;41:159-165. doi: 10.1016/j.carrev.2021.12.009. Epub 2021 Dec 16.

Abstract

Transcatheter aortic valve implantation [TAVI] represents a paradigm shift in therapeutic options for patients with severe aortic stenosis [AS]. In less than 20 years, TAVI has rapidly disseminated to include a significant proportion of AS patients. The number of AS patients needing TAVI is expected to further increase. Since there is a limited number of centers performing TAVI, wait times are expected to increase. This might have a critical impact of AS patient life as mortality rate of AS patients awaiting TAVI, is substantial, ranging from 2 to 10%. With time, as more patients were treated, improved experience, better imaging and devices, this technology became safer with more reliable results. Today most TAVI complications are related to vascular access [4-6%] and there is less need for emergency thoracic bail out [0.2-0.5%]. In this review, we summarize the prognosis while waiting, the outcomes of patients undergoing TAVI at institutions without on-site cardiac surgery departments and the data describing rates and outcomes of TAVI patients requiring treatment of intra-procedural life-threatening complications. Similar to coronary interventions in the past, TAVI should be considered also in centers without on-site cardiac surgery departments under certain conditions such as, experienced operators, heart team discussion, well established imaging modalities, skilled and qualified support personal, and adequate pre- and post-care facility.

摘要

经导管主动脉瓣植入术 [TAVI] 代表了治疗严重主动脉瓣狭窄 [AS] 患者的治疗选择的范式转变。在不到 20 年的时间里,TAVI 迅速传播,包括了相当一部分 AS 患者。需要 TAVI 的 AS 患者数量预计将进一步增加。由于进行 TAVI 的中心数量有限,预计等待时间将延长。这可能会对 AS 患者的生命产生重大影响,因为等待 TAVI 的 AS 患者的死亡率相当高,范围为 2%至 10%。随着时间的推移,随着越来越多的患者接受治疗,经验的积累、更好的成像和设备,这项技术变得更加安全,结果也更加可靠。如今,大多数 TAVI 并发症与血管通路有关 [4-6%],需要紧急开胸抢救的情况较少 [0.2-0.5%]。在这篇综述中,我们总结了等待时的预后、在没有现场心脏手术部门的机构中接受 TAVI 治疗的患者的结果,以及描述需要治疗术中危及生命并发症的 TAVI 患者的发生率和结果的数据。与过去的冠状动脉介入治疗类似,在某些情况下,如经验丰富的操作人员、心脏团队讨论、成熟的成像方式、熟练和合格的支持人员以及充足的术前和术后护理设施,也应考虑在没有现场心脏手术部门的中心进行 TAVI。

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