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外翻式内膜切除术——一种治疗髂外动脉闭塞性疾病的替代方法。

Eversion Endarterectomy - An Alternative Approach to Occlusive External Iliac Artery disease.

机构信息

Department of Vascular Surgery, Mater Misericordiae University Hospital, Dublin, Republic of Ireland.

Department of Vascular Surgery, Mater Misericordiae University Hospital, Dublin, Republic of Ireland.

出版信息

Ann Vasc Surg. 2022 Jul;83:290-297. doi: 10.1016/j.avsg.2021.12.005. Epub 2021 Dec 22.

Abstract

OBJECTIVES

While endovascular intervention is the recommended first option for management of common iliac artery (CIA) lesions, it lacks durable patency for Trans-Atlantic Inter-Society Consensus (TASC)-II C and D lesions involving the external iliac artery (EIA). Aorto-femoral bypass is a durable option but is unsuitable in patients with significant co-morbidities. Eversion endarterectomy provides an alternative to both endovascular and extensive open aortoiliac reconstruction for occlusive EIA disease.

MATERIALS AND METHODS

A single-center, retrospective review (2000-2020) of all patients undergoing eversion endarterectomy for EIA disease was undertaken. Demographic, clinical, operative and follow-up data were recorded.

RESULTS

Fifty eversion endarterectomies were performed in 47 patients. The median age was 65.0 years (range 46-82) and 66.6% were male. Sixty-eight percent (n = 34) were ASA grade 3. Indications for intervention were disabling claudication (44%) and critical limb ischaemia (56%). Angiography demonstrated 22 TASC C and 28 TASC D lesions. The median follow-up was 18.5 months (range 0-149). The technical success rate was 100%, and 84% (n = 42) experienced an immediate symptomatic improvement. Primary and primary-assisted patency at one, three and five years was 86%, 82% and 74%, and 100%, 96% and 92%, respectively. The five-year limb salvage rate was 96%. Eight limbs required reintervention to maintain patency, either by open (n = 2), endovascular (n = 3) or hybrid approach (n = 3). Thirty-day mortality was 2% (n = 1) with 10% (n = 5) experiencing a procedure-related morbidity. All-cause mortality was 38% (n = 19) during the follow-up period.

CONCLUSIONS

Eversion endarterectomy is a safe, effective alternative treatment for occlusive EIA disease. This study reports durable patency at five years and low perioperative morbidity and mortality.

摘要

目的

虽然血管内介入治疗是治疗常见髂动脉(CIA)病变的首选方法,但对于涉及髂外动脉(EIA)的 TASC-II C 和 D 病变,其通畅性缺乏持久性。主动脉-股动脉旁路术是一种持久的选择,但不适合有严重合并症的患者。外翻内膜切除术是血管内和广泛开放主髂动脉重建治疗闭塞性 EIA 疾病的另一种选择。

材料和方法

回顾性分析了 2000 年至 2020 年间在我院接受外翻内膜切除术治疗 EIA 疾病的所有患者的临床资料。记录了人口统计学、临床、手术和随访数据。

结果

47 例患者共行外翻内膜切除术 50 例。中位年龄为 65.0 岁(范围 46-82 岁),66.6%为男性。68%(n=34)为 ASA 分级 3 级。干预指征为:严重跛行(44%)和严重肢体缺血(56%)。血管造影显示 22 例 TASC C 病变和 28 例 TASC D 病变。中位随访时间为 18.5 个月(范围 0-149 个月)。技术成功率为 100%,84%(n=42)即刻症状改善。1、3、5 年的原发通畅率和原发性辅助通畅率分别为 86%、82%和 74%,100%、96%和 92%。5 年肢体存活率为 96%。8 条肢体需要再次介入治疗以维持通畅,其中开放治疗 2 例,血管内治疗 3 例,杂交治疗 3 例。30 天死亡率为 2%(n=1),10%(n=5)发生与手术相关的并发症。在随访期间,总死亡率为 38%(n=19)。

结论

外翻内膜切除术是治疗闭塞性 EIA 疾病的一种安全、有效的治疗方法。本研究报道了 5 年通畅率高,围手术期并发症和死亡率低。

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