Spindler Philipp, Fiss Ingo, Giese Henrik, Hermann Elvis, Lemcke Johannes, Schuhmann Martin U, Thomale Ulrich-Wilhelm, Schaumann Andreas
Division of Pediatric Neurosurgery, Department of Neurosurgery, Campus Virchow Klinikum, Charité Universitätsmedizin Berlin, Berlin, Germany.
Division of Pediatric Neurosurgery, Department of Neurosurgery, Universitätsmedizin Göttingen, Göttingen, Germany.
World Neurosurg. 2022 Mar;159:e221-e231. doi: 10.1016/j.wneu.2021.12.036. Epub 2021 Dec 23.
Accurate placement of a ventricular catheter (VC) is crucial to reduce the risk of shunt failure. In the randomized, prospective, multicenter GAVCA (guided application of ventricular catheters) trial, which evaluated the quality of VC placement, the subgroup of patients with detailed length-marked VCs (dVCs) reflected a difference in the primary endpoint of optimal VC placement compared with the subgroup of patients with simplified length-marked VCs (sVCs). The objective of the present analysis was to compare the dVC and sVC groups and the smartphone-assisted guidance technique (GA) with the standard freehand technique (FH) for VC placement.
We performed a further analysis of the GAVCA trial in 2 steps. First, we compared the dVCs, which provided a detailed distance from the tip to the base (3-13 cm) in 0.5-cm intervals, with the sVCs with a length indication at 5 and 10 cm from the tip to base. Second, we compared the GA technique with the FH in the dVC group.
The data from 137 patients (104 dVC patients vs. 33 sVC patients) were eligible for the present analysis. Optimal VC placement was achieved in 72.1% of the dVC group and 39.4% of the sVC group (odds ratio, 3.9; 95% confidence interval, 1.7-9.3; P ≤ 0.001). In addition, we performed a subgroup analysis of the 104 dVC patients concerning the accuracy of catheter placement using 2 different techniques (GA, n = 54; and FH, n = 50). Optimal catheter placement was achieved in 81.5% of the GA group and 62.0% of the FH group (odds ratio, 2.7; 95% confidence interval, 1.1-6.8; P = 0.03). VC placement using the GA technique was successful in all patients at the primary puncture. In contrast, for 8.7% of the patients in the FH group, multiple attempts were necessary (P = 0.03).
The results from the present analysis suggest that the combination of a GA technique and the use of a dVC will improve the rate of accurate VC placement. Compared with the FH technique, patient safety was increased by the reduction of unsuccessful VC placement attempts using the GA technique and dVCs.
准确放置脑室导管(VC)对于降低分流失败风险至关重要。在评估VC放置质量的随机、前瞻性、多中心GAVCA(脑室导管引导应用)试验中,与使用简化长度标记脑室导管(sVC)的患者亚组相比,使用详细长度标记脑室导管(dVC)的患者亚组在最佳VC放置的主要终点上表现出差异。本分析的目的是比较dVC组和sVC组以及智能手机辅助引导技术(GA)与标准徒手技术(FH)在VC放置中的效果。
我们分两步对GAVCA试验进行了进一步分析。首先,我们将能以0.5厘米间隔提供从尖端到基部详细距离(3 - 13厘米)的dVC与在距尖端到基部5厘米和10厘米处有长度指示的sVC进行比较。其次,我们在dVC组中比较了GA技术和FH技术。
137例患者的数据(104例dVC患者与33例sVC患者)符合本分析要求。dVC组中72.1%实现了最佳VC放置,sVC组中这一比例为39.4%(优势比,3.9;95%置信区间,1.7 - 9.3;P≤0.001)。此外,我们对104例dVC患者使用两种不同技术(GA组,n = 54;FH组,n = 50)进行导管放置准确性的亚组分析。GA组中81.5%实现了最佳导管放置,FH组中这一比例为62.0%(优势比,2.7;95%置信区间,1.1 - 6.8;P = 0.03)。使用GA技术进行VC放置在所有患者的首次穿刺时均成功。相比之下,FH组中有8.7%的患者需要多次尝试(P = 0.03)。
本分析结果表明,GA技术与dVC的结合将提高准确VC放置的成功率。与FH技术相比,使用GA技术和dVC减少了VC放置失败的尝试,提高了患者安全性。