重组人白细胞介素-2静脉输注后在大鼠体内的毒性
The toxicity of recombinant human interleukin-2 in rats following intravenous infusion.
作者信息
Matory Y L, Chang A E, Lipford E H, Braziel R, Hyatt C L, Rosenberg S A
出版信息
J Natl Med Assoc. 1987 May;79(5):537-41.
Abstract
Studies of recombinant interleukin-2 (RIL-2) administered by continuous intravenous infusion revealed hepatocellular toxicity and redistribution of lymphoid cells. This finding was different from the normal findings seen in rats receiving comparable infusions of the vehicle.
摘要
对通过持续静脉输注给予重组白细胞介素-2（RIL-2）的研究显示出肝细胞毒性以及淋巴细胞的重新分布。这一发现与接受同等剂量溶媒输注的大鼠的正常表现不同。
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The toxicity of recombinant human interleukin-2 in rats following intravenous infusion.重组人白细胞介素-2静脉输注后在大鼠体内的毒性
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Augmentation of the anti-tumor therapeutic efficacy of long-term cultured T lymphocytes by in vivo administration of purified interleukin 2.通过体内给予纯化的白细胞介素2增强长期培养的T淋巴细胞的抗肿瘤治疗效果。
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