mNUTRIC评分在新型冠状病毒肺炎危重症患者营养风险评估及预后预测中的应用：一项回顾性观察研究
Use of mNUTRIC-Score for Nutrition Risk Assessment and Prognosis Prediction in Critically Ill Patients with COVID-19: A Retrospective Observational Study.
作者信息
Yanowsky-Escatell Francisco G, Ontiveros-Galindo Areli L, Arellano-Arteaga Kevin J, Román-Pintos Luis M, Andrade-Castellanos Carlos A, Hernández-Corona Diana M, González-Heredia Tonatiuh, Villegas-Rivera Geannyne
机构信息
Departamento de Medicina Interna, Hospital Civil de Guadalajara Dr. Juan I. Menchaca, Guadalajara, Jalisco, Mexico.
Programa de Doctorado en Investigación Multidisciplinaria en Salud, Centro Universitario de Tonalá, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico.
出版信息
Crit Care Res Pract. 2021 Dec 22;2021:5866468. doi: 10.1155/2021/5866468. eCollection 2021.
INTRODUCTION
Nutritional risk is highly prevalent in patients with COVID-19. Relevant data on nutritional assessment in the critically ill population are scarce. This study was conducted to evaluate the modified Nutrition Risk in the Critically Ill (mNUTRIC)-Score as a mortality risk factor in mechanically ventilated patients with COVID-19.
METHODS
We conducted this retrospective observational study in critically ill patients with COVID-19. Patients' characteristics and clinical information were obtained from electronic medical records. The nutritional risk for each patient was assessed at the time of mechanical ventilation using the mNUTRIC-Score. The major outcome was 28-day mortality.
RESULTS
Ninety-eight patients were analyzed (mean age, 57.22 ± 13.66 years, 68.4% male); 46.9% of critically ill COVID-19 patients were categorized as being at high nutrition risk (mNUTRIC-Score of ≥5). A multivariate logistic regression model indicated that high nutritional risk has higher 28-day hospital mortality (OR = 4.206, 95% CI: 1.147-15.425, =0.030). A multivariate Cox regression analysis showed that high-risk mNUTRIC-Score had a significantly increased full-length mortality risk during hospitalization (OR = 1.991, 95% CI: 1.219-3.252, =0.006).
CONCLUSION
The mNUTRIC-Score is an independent mortality risk factor during hospitalization in critically ill COVID-19 patients.
引言
营养风险在新冠病毒疾病（COVID-19）患者中极为普遍。危重症人群营养评估的相关数据匮乏。本研究旨在评估改良的危重症患者营养风险（mNUTRIC）评分作为COVID-19机械通气患者死亡风险因素的情况。
方法
我们对COVID-19危重症患者进行了这项回顾性观察研究。患者的特征和临床信息从电子病历中获取。在机械通气时使用mNUTRIC评分评估每位患者的营养风险。主要结局是28天死亡率。
结果
分析了98例患者（平均年龄57.22±13.66岁，68.4%为男性）；46.9%的COVID-19危重症患者被归类为高营养风险（mNUTRIC评分≥5）。多因素逻辑回归模型表明，高营养风险的患者28天医院死亡率更高（比值比[OR]=4.206，95%置信区间[CI]：1.147-15.425，P=0.030）。多因素Cox回归分析显示，高风险mNUTRIC评分在住院期间全因死亡风险显著增加（OR=1.991，95%CI：1.219-3.252，P=0.006）。
结论
mNUTRIC评分是COVID-19危重症患者住院期间独立的死亡风险因素。
Zotero 插件