Interventional Cardiology Unit, Hospital universitario Lucus Augusti, 27003 Lugo, Galicia, Spain.
Rev Cardiovasc Med. 2021 Dec 22;22(4):1357-1360. doi: 10.31083/j.rcm2204141.
The pathophysiology of Takotsubo Syndrome has not yet been precisely defined. Different hypotheses have been proposed, including cardiotoxicity due to catecholaminergic hormone release, metabolic disorders, coronary microvascular dysfunction and epicardial coronary artery spasm. Invasive coronary physiology is considered the cornerstone to understand physiological assessment of coronary blood flow in this setting. We have reviewed most important studies in coronary invasive physiology in this field to update the state of the art in TakoTsubo Syndrome.
Takotsubo 综合征的病理生理学尚未得到明确界定。已经提出了不同的假说，包括儿茶酚胺激素释放引起的心毒性、代谢紊乱、冠状动脉微血管功能障碍和心外膜冠状动脉痉挛。侵入性冠状动脉生理学被认为是理解这种情况下冠状动脉血流生理评估的基石。我们回顾了该领域中冠状动脉侵入性生理学的大多数重要研究，以更新 Takotsubo 综合征的最新技术状态。
