Clinical and Interventional Cardiology Unit, Sant'Ambrogio Cardio-Thoracic Center, 20149 Milan, Italy.
Interventional Cardiology Unit, Fondazione Poliambulanza, 25124 Brescia, Italy.
Rev Cardiovasc Med. 2021 Dec 22;22(4):1421-1428. doi: 10.31083/j.rcm2204147.
Coronary bifurcation lesion (CBL) is a common but challenging scenario in percutaneous coronary interventions. Drug-coated balloons (DCBs) are modern devices with attractive perspective in CBL treatment. In-stent restenosis, small vessel and diffuse de-novo coronary artery disease have been, so far, considered the ideal scenario for DCBs application. Studies assessing DCBs in de-novo CBL demonstrated the safety and efficacy of this strategy. However, the heterogeneity of the study populations and the presence of methodological limitations prevent from drawing definite recommendations. Considering that the best treatment of bifurcations has not yet been defined, the "leaving nothing behind" philosophy will be the topic of future studies.
冠状动脉分叉病变（CBL）是经皮冠状动脉介入治疗中常见但具有挑战性的情况。药物涂层球囊（DCB）是一种现代器械，在 CBL 治疗中有很大的应用前景。支架内再狭窄、小血管和弥漫性新发冠状动脉疾病迄今为止被认为是 DCB 应用的理想适应证。评估 DCB 在新发 CBL 中的应用的研究表明了该策略的安全性和有效性。然而，研究人群的异质性和方法学局限性的存在阻碍了明确的推荐意见的形成。鉴于分叉病变的最佳治疗方法尚未确定，“不遗留任何东西”的理念将是未来研究的主题。
