Department of Nephrology and Dialysis, University Hospital Centre Split, 21000 Split, Croatia.
Department of Internal Medicine, University of Split School of Medicine, 21000 Split, Croatia.
Nutrients. 2021 Dec 15;13(12):4479. doi: 10.3390/nu13124479.
Depression has been addressed as a predictor of worse outcomes in kidney transplant recipients (KTRs). Nutritional status plays a great role in treatment of this population. The Mediterranean diet (MeDi) has been associated with lower levels of depressive symptoms. The aim of this cross-sectional study was to determine the rate of depression and its correlations to nutritional status and dietary habits according to the MeDi in Dalmatian KTRs. We included 115 KTRs, and data about body composition and anthropometric, laboratory and clinical parameters were obtained for each study participant. The Beck Depression Inventory-II (BDI-II) questionnaire was used to assess depressive symptoms and the Mediterranean Diet Serving Score (MDSS) was used to assess adherence to the MeDi. We found the presence of depressive symptoms in 21.73% of the Dalmatian KTRs. BDI-II score was reciprocally associated with fat mass, trunk visceral fat, anthropometric parameters of obesity, triglyceride levels and olive oil consumption. Inverse associations were found between BDI-II score and skeletal muscle mass, handgrip strength, MCV, hemoglobin levels and consumption of fish and white meat, as suggested by the MeDi. Our results showed the interconnections between nutritional status, dietary habits and depression in Dalmatian KTRs.
抑郁已被视为肾移植受者(KTR)预后不良的预测因素。营养状况在该人群的治疗中起着重要作用。地中海饮食(MeDi)与较低水平的抑郁症状有关。本横断面研究的目的是确定达尔马提亚 KTR 中抑郁的发生率及其与营养状况和饮食习惯的相关性,以 MeDi 为依据。我们纳入了 115 名 KTR,为每位研究参与者获得了关于身体成分和人体测量、实验室和临床参数的数据。使用贝克抑郁量表二(BDI-II)问卷评估抑郁症状,使用地中海饮食服务评分(MDSS)评估对 MeDi 的依从性。我们发现 21.73%的达尔马提亚 KTR 存在抑郁症状。BDI-II 评分与脂肪量、躯干内脏脂肪、肥胖的人体测量参数、甘油三酯水平和橄榄油的消耗呈反向相关。BDI-II 评分与骨骼肌质量、握力、MCV、血红蛋白水平和鱼类及白肉的摄入呈负相关,这与 MeDi 所建议的一致。我们的研究结果表明,达尔马提亚 KTR 中的营养状况、饮食习惯和抑郁之间存在相互联系。