Department of Organ Transplantation Center, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui, China.
Department of Organ Transplantation Center, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui, China.
Transplant Proc. 2022 Jan-Feb;54(1):158-160. doi: 10.1016/j.transproceed.2021.11.016. Epub 2021 Dec 24.
Severe neurologic complications after chronic liver disease greatly affect the patient's quality of life. Hepatic myelopathy (HM) is a rare but devastating disease, in chronic liver disease. The limbs of patients with HM show slowly progressive symmetrical spastic paralysis without sensory loss. Management of this severe neurologic complication is challenging. These patients often require timely and effective clinical intervention. Although liver transplantation is one of the effective treatments for HM, the prognosis of these patients remains poor, many of them spend their lives in wheelchairs. Here, we report a patient with HM after hepatitis B virus related decompensated liver cirrhosis who recovered well after liver transplant. This work was carried out in compliance with the Helsinki Congress and the Declaration of Istanbul.
慢性肝脏疾病后出现严重的神经系统并发症极大地影响了患者的生活质量。肝性脊髓病(HM)是一种罕见但具有破坏性的疾病,在慢性肝脏疾病中。HM 患者的四肢表现为进行性缓慢对称痉挛性瘫痪,无感觉丧失。管理这种严重的神经系统并发症具有挑战性。这些患者通常需要及时有效的临床干预。虽然肝移植是 HM 的有效治疗方法之一,但这些患者的预后仍然较差,许多患者终身坐在轮椅上。在这里,我们报告了一例乙型肝炎病毒相关失代偿性肝硬化后发生 HM 的患者,肝移植后恢复良好。这项工作符合赫尔辛基大会和伊斯坦布尔宣言的规定。