AP-HP Center, University of Paris, Department of Psychiatry, Regional Resource Center of old age psychiatry, Issy-les-Moulineaux 92130, France.
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, 2213 Elba Street, Durham, NC, 27710, United States.
Psychiatry Res. 2022 Feb;308:114339. doi: 10.1016/j.psychres.2021.114339. Epub 2021 Dec 15.
Data are scarce regarding the clinical factors associated with utilization of long-term care facilities among older adults with schizophrenia. In this multicenter study, we sought to examine potential clinical differences between older adults with schizophrenia who are living in a long-term care facility and their community-dwelling counterparts.
We used data from the French Cohort of individuals with Schizophrenia Aged 55-years or more (CSA) study, a large multicenter sample of older adults with schizophrenia (N = 353).
The prevalence of long-term care utilization was 35.1% of older patients with schizophrenia. Living in a long term care facility was significantly and independently associated with higher level of depression (Adjusted odds ratio (AOR) [95%CI]=1.97 [1.06-3.64]), lower cognitive (AOR [95%CI]=0.94 [0.88-0.99]) and global functioning (AOR [95%CI]=0.97 [0.95-0.99]), greater lifetime number of hospitalizations in a psychiatric department (AOR [95%CI]=2.30 [1.18-4.50]), not having consulted a general practitioner in the past year (AOR [95%CI]=0.28 [0.0.14-0.56]), urbanicity (AOR [95%CI]=2.81 [1.37-5.80]), and older age (AOR [95%CI]=1.08 [1.03-1.13]).
Older patients with schizophrenia who live in long-term care facilities appear to belong to a distinct group, marked by a more severe course of illness with higher level of depression and more severe cognitive deficits than older patients with schizophrenia living in other settings. Our study highlights the need of early assessment and management of depression and cognitive deficits in this population and the importance of monitoring closely this vulnerable population.
有关老年精神分裂症患者使用长期护理设施的临床相关因素的数据较为匮乏。在这项多中心研究中,我们旨在研究居住在长期护理机构的老年精神分裂症患者与居住在社区的患者之间潜在的临床差异。
我们使用了法国年龄在 55 岁及以上的精神分裂症患者队列(CSA)研究的数据,这是一项针对老年精神分裂症患者的大型多中心样本(N=353)。
老年精神分裂症患者中,长期护理的使用率为 35.1%。居住在长期护理机构与较高水平的抑郁(调整后的优势比(95%CI)=1.97[1.06-3.64])、较低的认知(95%CI)=0.94[0.88-0.99])和整体功能(95%CI)=0.97[0.95-0.99])、更多的一生中在精神科住院的次数(95%CI)=2.30[1.18-4.50])、过去一年未看过全科医生(95%CI)=0.28[0.0.14-0.56])、城市(95%CI)=2.81[1.37-5.80])和年龄较大(95%CI)=1.08[1.03-1.13])独立相关。
居住在长期护理机构的老年精神分裂症患者似乎属于一个独特的群体,其疾病严重程度更高,抑郁程度更高,认知功能障碍更严重,而居住在其他环境中的老年精神分裂症患者则较轻。我们的研究强调了在这一人群中早期评估和管理抑郁和认知缺陷的必要性,以及密切监测这一弱势群体的重要性。