Department of Internal Medicine, University of Health Sciences, Tepecik Education and Research Hospital, Izmir, Turkey.
Department of Gastroenterology, Dokuz Eylül University School of Medicine, Izmir, Turkey.
Acta Gastroenterol Belg. 2021 Oct-Dec;84(4):571-576. doi: 10.51821/84.4.007.
BACKGROUND/AIMS: In this study, we examine the utility of Bedside Index of Severity in Acute Pancreatitis (BISAP), which is an increasingly more commonly used simple and practical novel scoring system for predicting the prognosis and severity of the disease at presentation.
Consecutive patients diagnosed with AP between January 2013 and December 2020 were evaluated retrospectively. The AP severity was assessed using the revised Atlanta classification (RAC). BISAP score, demographic characteristics, pancreatitis etiology, pancreatitis history, duration of hospital stay, and mortality rates of the patients were recorded.
A total of 1000 adult patients were included, of whom 589 (58.9%) were female and 411 (41.1%) were male. The mean age in female and male patients was 62.15 ± 17.79 and 58.1 ± 16.33 years, respectively (p >0.05). The most common etiological factor was biliary AP (55.8%), followed by idiopathic AP (23%). Based on RAC, 389 (38.9%), 418 (41.8%), and 193 (19.3%) patients had mild, moderate, and severe AP. Of the 1000 patients, 42 (4.2%) died. Significant predictors of mortality included advanced age (>65 y) (p=0.003), hypertension (p=0.007), and ischemic heart disease (p=0.001). A BISAP score of ≥3 had a sensitivity, specificity, positive predictive value, and negative predictive value (NPV) of 79.79%, 91.57%, 69.37%, and 94.99%, respectively, for determining SAP patients according to RAC.
BISAP is an effective scoring system with a high NPV in predicting the severity of AP in the early course of the disease in a Turkish population.
背景/目的：本研究旨在检验床边严重度指数（BISAP）在预测疾病发病时的预后和严重程度方面的应用价值。BISAP 是一种越来越常用的简单实用的新型评分系统。
回顾性评估了 2013 年 1 月至 2020 年 12 月期间连续诊断为 AP 的患者。使用修订后的亚特兰大分类（RAC）评估 AP 严重程度。记录 BISAP 评分、人口统计学特征、胰腺炎病因、胰腺炎病史、住院时间和死亡率。
共纳入 1000 例成年患者，其中 589 例（58.9%）为女性，411 例（41.1%）为男性。女性和男性患者的平均年龄分别为 62.15±17.79 岁和 58.1±16.33 岁（p＞0.05）。最常见的病因是胆源性 AP（55.8%），其次是特发性 AP（23%）。根据 RAC，389 例（38.9%）、418 例（41.8%）和 193 例（19.3%）患者患有轻度、中度和重度 AP。1000 例患者中，42 例（4.2%）死亡。死亡的显著预测因素包括高龄（＞65 岁）（p=0.003）、高血压（p=0.007）和缺血性心脏病（p=0.001）。BISAP 评分≥3 时，根据 RAC 确定 SAP 患者的敏感性、特异性、阳性预测值和阴性预测值（NPV）分别为 79.79%、91.57%、69.37%和 94.99%。
BISAP 是一种有效的评分系统，在预测土耳其人群疾病早期的 AP 严重程度方面具有较高的 NPV。
