Sviridenko N Yu, Sheremeta M S, Belovalova I M, Melnichenko G A
Scientific Medical Research Center of Endocrinology, Moscow, Russia.
Vestn Oftalmol. 2021;137(6):128-135. doi: 10.17116/oftalma2021137061128.
Graves' disease (GD) is an autoimmune disease that is often complicated by thyroid eye disease (TED). Clinical presentations of TED can develop simultaneously with the manifestation of GD, after the manifestation of GD amid treatment, and before the development of thyrotoxicosis. Treatment of such patients is a difficult task, because on the one hand, it is necessary to take into account the clinical picture of thyrotoxicosis, and on the other - the symptoms of eye damage. The combination of the two pathologies determines the need for simultaneous treatment of GD and TED, and the choice of a treatment method for GD will depend on the manifestations of TED. This article presents current views on the treatment of GD with concomitant TED. The choice of GD treatment method will be largely determined by the clinical manifestations of TED and will be conducted jointly by endocrinologists and ophthalmologists.
格雷夫斯病(GD)是一种自身免疫性疾病,常并发甲状腺眼病(TED)。TED的临床表现可与GD的表现同时出现、在GD治疗期间出现,以及在甲状腺毒症发生之前出现。治疗这类患者是一项艰巨的任务,因为一方面,需要考虑甲状腺毒症的临床表现,另一方面,要考虑眼部损伤的症状。两种病症的结合决定了需要同时治疗GD和TED,而GD治疗方法的选择将取决于TED的表现。本文介绍了目前关于合并TED的GD治疗的观点。GD治疗方法的选择在很大程度上取决于TED的临床表现,将由内分泌科医生和眼科医生共同进行。