Kong De-Hai, Zhao Yong-Jie, Guan Guo-Feng, Deng Ming-Ming, Yin Gang, Sun Guang-Chao
Binzhou Medical University Hospital, Binzhou 256600, Shandong, China.
Zhongguo Gu Shang. 2021 Dec 25;34(12):1182-5. doi: 10.12200/j.issn.1003-0034.2021.12.017.
To evaluate the clinical efficacy of local infiltration anesthesia of ropivacaine combined with compound betamethasone for postoperative analgesia in patients with hallux valgus.
From September 2019 to December 2020, 48 patients with hallux valgus were treated surgically. According to different postoperative analgesia methods, the patients were divided into combined local infiltration group and intravenous analgesia pump group. There were 24 cases, in the combined local infiltration group including 2 males and 22 females;the age ranged from 21 to 78 years old, with an average of (58.3±7.7) years old;soft tissue release and chevron osteotomy were performed in 15 cases and metatarsophalangeal joint fusion in 9 cases;immediately after operation, 20 ml of ropivacaine combined with compound betamethasone mixed diluent was used for local infiltration anesthesia once. There were 24 patients in intravenous analgesia pump group, including 3 males and 21 females;the age ranged from 23 to 81 years old, with an average of(56.8±8.3) years old;soft tissue release and Chevron osteotomy were performed in 17 cases and metatarsophalangeal joint fusion in 7 cases;immediately after operation, intravenous analgesia pump was used for analgesia. The basic flow was 2 ml / h;the self control dose was 0.5 ml;and the locking time was 15 min. Visual analogue scale (VAS) was recorded at 12, 24, 48 and 72 hours after operation;and the VAS was recorded at 24 hours after operation. The occurrence of adverse drug reactions at 0 to 12 hours, 12 to 24 hours and 24 to 48 hours after operation were recorded;and the healing of incision was recorded.
All patients were followed up, and the duration ranged from 14 to 17 days, with a mean of (14.60±0.92) days. There was significantdifference in VAS at 12, 24 and 48 hours between the combined local infiltration group and the intravenous analgesia pump group(<0.05). There was no significant difference in VAS between the two groups 72 hours after operation (>0.05). There was no significant difference in the number of adverse drug reactions between the two groups at 0 to 12 hours after operation (>0.05);there was significant difference in the number of adverse drug reactions 12 to 24 hours after operation (<0.05). No adverse drug reactions occurred in both groups 24 to 48 hours after operation. There was no significant difference in the grade of knife edge healing between the two groups after suture removal (>0.05).
Compared with intravenous analgesia pump group, ropivacaine combined with compound betamethasone can significantly reduce postoperative wound pain without increasing adverse drug reactions, and does not increase wound infection.
评价罗哌卡因联合复方倍他米松局部浸润麻醉用于拇外翻患者术后镇痛的临床疗效。
选取2019年9月至2020年12月手术治疗的48例拇外翻患者。根据术后不同镇痛方法将患者分为局部浸润联合组和静脉镇痛泵组。局部浸润联合组24例,其中男2例,女22例;年龄21~78岁,平均(58.3±7.7)岁;行软组织松解及契形截骨术15例,跖趾关节融合术9例;术后即刻采用20 ml罗哌卡因联合复方倍他米松混合稀释液行局部浸润麻醉1次。静脉镇痛泵组24例,其中男3例,女21例;年龄23~81岁,平均(56.8±8.3)岁;行软组织松解及契形截骨术17例,跖趾关节融合术7例;术后即刻采用静脉镇痛泵镇痛,基础流量2 ml/h,自控剂量0.5 ml,锁定时间15 min。分别于术后12、24、48、72 h记录视觉模拟评分(VAS);于术后24 h记录VAS。记录术后0至12 h、12至24 h、24至48 h药物不良反应发生情况;记录切口愈合情况。
所有患者均获随访,随访时间14~17天,平均(14.60±0.92)天。局部浸润联合组与静脉镇痛泵组术后12、24、48 h的VAS评分比较,差异有统计学意义(<0.05)。术后72 h两组VAS评分比较,差异无统计学意义(>0.05)。术后0至12 h两组药物不良反应发生例数比较,差异无统计学意义(>0.05);术后12至24 h两组药物不良反应发生例数比较,差异有统计学意义(<0.05)。术后24至48 h两组均未发生药物不良反应。拆线后两组切口愈合分级比较,差异无统计学意义(>0.05)。
与静脉镇痛泵组比较,罗哌卡因联合复方倍他米松可显著减轻术后伤口疼痛,且不增加药物不良反应及伤口感染。