Shiraz Transplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Clinical Pharmacy, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
BMC Surg. 2021 Dec 30;21(1):446. doi: 10.1186/s12893-021-01454-2.
Various abdominal pathologies end up with surgical resection of small intestine. When the small intestine remnant is too short for adequate fluid and micronutrients absorption, short bowel syndrome is diagnosed. The disabling condition needs a multidisciplinary approach to design parenteral nutrition, care for thrombotic, hepatic and infectious complications and gradually wean the patient from parenteral nutrition. Various surgical techniques have been introduced to increase absorptive mucosa and enhance the intestinal adaptation process. Serial transverse enteroplasty and nipple valve reconstruction are among the procedures, which will be discussed in the current article.
Herein, we presented 5 cases of short bowel syndrome as a consequence of abdominal laparotomies, patients were referred to our center to receive parenteral nutrition and to be prepared for the final autologous gastrointestinal reconstruction or intestinal transplantation, if indicated.
Patient's age, performance status and bowel remnant length determines the appropriate technique for autologous gastrointestinal reconstruction. Serial transverse enteroplasty is designed to increase bowel's length by creating zigzag patterns through dilated bowel loops. Presence of ileocecal valve is crucial to delay intestinal transit time and to prevent colonic bacterial transfer to ileum. Patient's with ileocecal valve loss benefit from creating an artificial valve, namely, nipple valve.
各种腹部病变最终需要进行小肠切除术。当小肠残余太短,无法充分吸收液体和微量营养素时,就会诊断出短肠综合征。这种使人衰弱的疾病需要多学科方法来设计肠外营养,护理血栓、肝脏和感染性并发症,并逐渐使患者摆脱肠外营养。已经引入了各种手术技术来增加吸收性黏膜并增强肠道适应过程。其中包括肠排列术和乳头瓣重建术,本文将对这些手术进行讨论。
本文介绍了 5 例因腹部剖腹术导致的短肠综合征患者,这些患者被转至我们中心接受肠外营养,并为最终的自体胃肠道重建或如果需要的话进行肠移植做准备。
患者的年龄、身体状况和肠残余长度决定了自体胃肠道重建的合适技术。肠排列术通过扩张肠袢来创建之字形图案来增加肠的长度。回盲瓣的存在对于延迟肠传输时间和防止结肠细菌转移到回肠至关重要。对于失去回盲瓣的患者,可受益于创建人工瓣膜,即乳头瓣。