Département d'oncologie radiothérapie, Institut universitaire du cancer de Toulouse-Oncopole (IUCT-oncopole), université Paul-Sabatier Toulouse III, 1, avenue Irène-Joliot-Curie, 31059 Toulouse cedex 9, France.
Département d'oncologie radiothérapie, Institut de cancérologie de Lorraine centre Alexis-Vautrin, 6, avenue de Bourgogne, CS 30519, 54519 Vandœuvre-lès-Nancy cedex, France.
Cancer Radiother. 2022 Feb-Apr;26(1-2):356-367. doi: 10.1016/j.canrad.2021.11.018. Epub 2021 Dec 27.
A third of children with cancer receive radiotherapy as part of their initial treatment, which represents 800 paediatric irradiations per year in France carried out in 15 specialized centres approved on the recommendations of the French national cancer institute in decreasing order of frequency, the types of cancer that require irradiation are: brain tumours, neuroblastomas, Ewing's sarcomas, Hodgkin's lymphomas, soft tissue sarcomas including rhabdomyosarcomas, and nephroblastomas. The treatment guidelines follow the recommendations of the French society for childhood cancers (SFCE) or the French and European prospective protocols. The therapeutic indications, the technical and/and ballistic choices of complex cases are frequently discussed during bimonthly paediatric radiotherapy technical web-conferences. All cancers combined, overall survival being 80%, long-term toxicity logically becomes an important concern, making the preparation of treatments complex. The irradiation methods include all the techniques currently available: 3D conformational irradiation, intensity modulation radiation therapy, irradiation under normal or hypofractionated stereotaxic conditions, brachytherapy and proton therapy. We present the update of the recommendations of the French society for radiation oncology on the indications, the technical methods of realization and the organisation and the specificities of paediatric radiation oncology.
三分之一的癌症患儿在初始治疗中接受放射治疗，这代表法国每年有 800 例儿科放射治疗，在 15 个专门中心进行，这些中心是根据法国国家癌症研究所的建议按频率降序排列的，需要放疗的癌症类型有：脑肿瘤、神经母细胞瘤、尤因肉瘤、霍奇金淋巴瘤、软组织肉瘤包括横纹肌肉瘤和肾母细胞瘤。治疗指南遵循法国儿童癌症学会 (SFCE) 或法国和欧洲前瞻性方案的建议。在每两个月举行一次的儿科放射治疗技术网络会议上，经常讨论复杂病例的治疗适应症、技术和/和弹道选择。所有癌症的总生存率为 80%，因此，长期毒性理所当然地成为一个重要关注点，这使得治疗方案的制定变得复杂。放射治疗方法包括目前所有可用的技术：三维适形放疗、强度调制放射治疗、常规或低分割立体定向放疗、近距离放疗和质子治疗。我们介绍了法国放射肿瘤学会关于适应症、实现技术方法以及组织和儿科放射肿瘤学特殊性的最新建议。
