转移性心膈角淋巴结（CPLNs）在卵巢癌患者中的现状：综述。
Current Status of Metastatic Cardiophrenic Lymph Nodes (CPLNs) in Patients With Ovarian Cancer: A Review.
机构信息
Department of General and Visceral Surgery, Krankenhaus Barmherzige Brüder, Regensburg, Germany;
Department of General and Visceral Surgery, Krankenhaus Barmherzige Brüder, Regensburg, Germany.
出版信息
Anticancer Res. 2022 Jan;42(1):13-24. doi: 10.21873/anticanres.15452.
BACKGROUND
One of the most common sites of extra-abdominal disease spread of advanced stage ovarian cancer is the cardiophrenic lymph node (CPLN) region. The role and impact of extra-abdominal cytoreduction is not obvious in patients with cardiophrenic lymph node metastases.
MATERIALS AND METHODS
We examined the relevant and currently available literature to determine the prognostic value and management of enlarged CPLNs in ovarian cancer patients.
RESULTS
Transdiaphragmatic excision of CPLNs or via video-assisted thoracoscopic surgery (VATS) is achievable without major complications. The most common postoperative complications were pleural effusion, pneumothorax and pneumonia. On preoperative CT scan, the cut-off size of suspicious CPLNs is not uniform and is indicated as 5 to 10 mm short-axis dimension.
CONCLUSION
CPLNs were detected in up to 60% of patients and malignancy was pathologically confirmed in 45-95% of the cases. The presence of enlarged CPLNs was found to be a negative prognostic factor, although its impact on progression-free and overall survival is not yet clarified and needs further investigation.
背景
晚期卵巢癌腹腔外转移最常见的部位之一是心膈角淋巴结（CPLN）区域。在有心膈角淋巴结转移的患者中，腹腔外减瘤术的作用和影响并不明显。
材料与方法
我们查阅了相关的现有文献，以确定在卵巢癌患者中，CPLN 增大的预后价值和处理方法。
结果
膈下切除 CPLN 或通过电视辅助胸腔镜手术（VATS）可在无重大并发症的情况下完成。最常见的术后并发症是胸腔积液、气胸和肺炎。在术前 CT 扫描中，可疑 CPLN 的截断大小并不统一，指示为 5 至 10 毫米短轴尺寸。
结论
多达 60%的患者可检测到 CPLN，其中 45-95%的病例经病理证实为恶性。CPLN 增大被认为是一个负预后因素，尽管其对无进展生存期和总生存期的影响尚不清楚，需要进一步研究。
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