Mitchell D L, Haipek C A, Clarkson J M
Int J Radiat Biol Relat Stud Phys Chem Med. 1987 Aug;52(2):201-5. doi: 10.1080/09553008714551661.
Using radioimmunoassays specific for (6-4) photoproducts and cyclobutane dimers, Xeroderma pigmentosum variant cells appear to have a normal capacity for the repair of each of these lesions. However, these assays measure an early stage in the repair pathway and we do not exclude the possibility that repair is not successfully completed following UV irradiation and excision of DNA photoproducts.
使用针对(6-4)光产物和环丁烷二聚体的放射免疫测定法,着色性干皮病变异细胞似乎对修复这些损伤中的每一种都具有正常能力。然而,这些测定法测量的是修复途径中的早期阶段,我们并不排除在紫外线照射和切除DNA光产物后修复未成功完成的可能性。