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狗的金孢子菌属皮下外瓶霉感染导致的皮下真菌病。

Subcutaneous phaeohyphomycosis due to Aureobasidium pullulans infection in a dog.

机构信息

Department of Veterinary Preventive, Faculty of Veterinary, Federal University of Pelotas, Pelotas/RS, Brasil.

Center for Technological Development, Faculty of Biotechnology, Federal University of Pelotas / RS, Brazil.

出版信息

Vet Ital. 2021 Jul 27;57(3). doi: 10.12834/VetIt.1821.9620.3.

Abstract

A case of subcutaneous phaeohyphomycosis in a dog with an ulcerative lesion on the right limb during a post-operative period of castration was described for the first time. The macroscopic and microscopic characteristics of the fungal colonies growth on the Sabouraud‑dextrose agar were detailed. The fungus was identified as Aureobasidium pullulans on the basis of the phenotypic analysis, which was confirmed by sequencing of the internal transcribed spacers (ITS) region of rDNA. The patient might have acquired the infection through traumatic inoculation by environmental contact, along with the immunological condition during the stressful period of postoperative. The spontaneous remission of the lesion was observed in five weeks without antifungal treatment. This work highlights the importance of considering the pathogenic potential of this environmental fungus and the need of including it in the differential diagnosis of cutaneous lesions in dogs.

摘要

首次描述了一例犬在阉割术后右肢出现溃疡病变时发生皮下外瓶霉病的病例。详细描述了沙保弱氏葡萄糖琼脂上真菌菌落生长的宏观和微观特征。根据表型分析,该真菌被鉴定为出芽短梗霉,这通过 rDNA 内转录间隔区(ITS)区域的测序得到了确认。患者可能是通过与环境接触的创伤性接种以及术后应激期的免疫状态而感染该病原体。未经抗真菌治疗,病变在五周内自行消退。本研究强调了考虑这种环境真菌的致病潜力以及在犬皮肤病变的鉴别诊断中纳入该真菌的重要性。

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