Division of Infectious Diseases, University Hospital of Geneva, Switzerland.
Division of Immunology and Allergy, Department of Medicine, University Hospital and Faculty of Medicine, Geneva, Switzerland. Division of Laboratory Medicine, Department of Diagnostic, Geneva University Hospitals, Geneva, Switzerland.
Swiss Med Wkly. 2022 Dec 6;152:40011. doi: 10.57187/smw.2022.40011.
We report on a case of probable invasive Auerobasidium spp. pulmonary infection in a patient with myelodysplastic syndrome. The patient was successfully treated with liposomal amphotericin B monotherapy, with transition to orally administered isavuconazole. This case shows an atypical initial radiological presentation with diffuse ground-glass opacities, as previously demonstrated in cases of Aureobasidium spp. hypersensitivity pneumonitis. Moreover this case further highlights the difficulties associated with the diagnosis and complexity in the management of Aureobasidium spp. infections.
我们报告了一例可能的侵袭性节菱孢属肺部感染病例,该患者患有骨髓增生异常综合征。患者经脂质体两性霉素 B 单药治疗成功,随后转为口服伊曲康唑。该病例的初始放射学表现不典型,表现为弥漫性磨玻璃影,此前已在节菱孢属过敏 性肺炎病例中得到证实。此外,该病例进一步强调了诊断和治疗节菱孢属感染相关的困难和复杂性。