Malwankar Jui, Son Hyeck-Soo, Chang David F, Dun Chen, Woreta Fasika, Prescott Christina, Makary Martin, Srikumaran Divya
Department of Ophthalmology, Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Altos Eye Physicians, Los Altos, California.
Ophthalmology. 2022 May;129(5):478-487. doi: 10.1016/j.ophtha.2021.12.015. Epub 2021 Dec 28.
To report the incidence of immediate sequential bilateral cataract surgery (ISBCS) and delayed sequential bilateral cataract surgery (DSBCS) and to identify factors associated with undergoing ISBCS.
Retrospective cohort study.
Medicare beneficiaries aged ≥ 65 who underwent ISBCS and DSBCS from 2011 through 2019.
Population-based analysis of the 100% Medicare fee-for-service carrier claims data. Logistic regression models were performed to evaluate factors associated with ISBCS.
Incidence of ISBCS and DSBCS; demographic, ocular, and medical characteristics associated with receipt of ISBCS; and rates of endophthalmitis and cystoid macular edema (CME) after ISBCS or DSBCS.
A total of 4014 (0.2%) ISBCS and 1 940 965 (99.8%) DSBCS patients were identified. Black (odds ratio [OR], 2.31; 95% confidence interval [CI], 2.06-2.59), Asian (OR, 1.82; 95% CI, 1.51-2.19), and Native American (OR, 2.42; 95% CI, 1.81-3.23) patients were more likely to receive ISBCS than White patients. Patients residing in rural areas showed a higher likelihood of ISBCS (OR, 1.26; 95% CI, 1.17-1.35) than patients in metropolitan areas. Patients undergoing surgery at a hospital, compared with an ambulatory setting (OR, 2.71; 95% CI, 2.53-2.89), were more likely to receive ISBCS. Patients with bilateral complex versus noncomplex cataract (OR, 3.23; 95% CI, 2.95-3.53) were more likely to receive ISBCS. Patients with a Charlson comorbidity index (CCI) of 1 to 2 (OR, 1.45; 95% CI, 1.29-1.62), 3 to 4 (OR, 1.70; 95% CI, 1.47-1.97), 5 to 6 (OR, 1.97; 95% CI, 1.62-2.39), and CCI ≥ 7 (OR, 1.97; 95% CI, 1.55-2.50) were more likely to receive ISBCS than those with a CCI of 0. In contrast, patients with glaucoma (OR, 0.82; 95% CI, 0.76-0.89), macular degeneration (OR, 0.75; 95% CI, 0.68-0.82), and macular hole or epiretinal membrane (OR, 0.55; 95% CI, 0.48-0.65) were less likely to undergo ISBCS than those without. Cumulatively, no significant difference was found in endophthalmitis rates within 42 days between ISBCS (1.74 per 1000 ISBCS procedures) and DSBCS (1.01 per 1000 DSBCS procedures; P = 0.15). Similarly, there was no significant cumulative difference between CME rates (P = 0.45) in ISBCS (1.79 per 100 ISBCS procedures) and DSBCS (1.96 per 100 DSBCS procedures).
Overall use of ISBCS among Medicare beneficiaries remained low over the past decade, although rates of endophthalmitis and CME were comparable to DSBCS. Race, geography, and systemic and ocular comorbidities were associated with receiving ISBCS. ISBCS represents a potential opportunity to improve access to cataract surgery.
报告即刻连续双侧白内障手术(ISBCS)和延迟连续双侧白内障手术(DSBCS)的发生率,并确定与接受ISBCS相关的因素。
回顾性队列研究。
2011年至2019年接受ISBCS和DSBCS的年龄≥65岁的医疗保险受益人。
基于人群对100%医疗保险按服务收费承运人索赔数据进行分析。采用逻辑回归模型评估与ISBCS相关的因素。
ISBCS和DSBCS的发生率;与接受ISBCS相关的人口统计学、眼部和医学特征;ISBCS或DSBCS后眼内炎和黄斑囊样水肿(CME)的发生率。
共识别出4014例(0.2%)ISBCS患者和1940965例(99.8%)DSBCS患者。黑人(比值比[OR],2.31;95%置信区间[CI],2.06 - 2.59)、亚洲人(OR,1.82;95%CI,1.51 - 2.19)和美洲原住民(OR,2.42;95%CI,1.81 - 3.23)患者比白人患者更有可能接受ISBCS。居住在农村地区的患者比大都市地区的患者接受ISBCS的可能性更高(OR,1.26;95%CI,1.17 - 1.35)。在医院接受手术的患者比在门诊环境接受手术的患者更有可能接受ISBCS(OR,2.71;95%CI,2.53 - 2.89)。双侧复杂性白内障患者比非复杂性白内障患者更有可能接受ISBCS(OR,3.23;95%CI,2.95 - 3.53)。Charlson合并症指数(CCI)为1至2(OR,1.45;95%CI,1.29 - 1.62)、3至4(OR,1.70;95%CI,1.47 - 1.97)、5至6(OR,1.97;95%CI,1.62 - 2.39)和CCI≥7(OR,1.97;95%CI,1.55 - 2.50)的患者比CCI为0的患者更有可能接受ISBCS。相比之下,患有青光眼(OR,0.82;95%CI,0.76 - 0.89)、黄斑变性(OR,0.75;95%CI,0.68 - 0.82)以及黄斑裂孔或视网膜前膜(OR,0.55;95%CI,0.48 - 0.65)的患者比没有这些疾病的患者接受ISBCS的可能性更小。累计来看,ISBCS(每1000例ISBCS手术中有1.74例)和DSBCS(每1000例DSBCS手术中有1.01例;P = 0.15)在42天内的眼内炎发生率无显著差异。同样,ISBCS(每100例ISBCS手术中有1.79例)和DSBCS(每100例DSBCS手术中有1.96例)的CME发生率也无显著累计差异(P = 0.45)。
在过去十年中,医疗保险受益人中ISBCS的总体使用率仍然较低,尽管眼内炎和CME的发生率与DSBCS相当。种族、地理位置以及全身和眼部合并症与接受ISBCS相关。ISBCS是改善白内障手术可及性的一个潜在机会。