Institute of Photomedicine, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Institute of Photomedicine, Shanghai Skin Disease Hospital, School of Medicine, Tongji University, Shanghai, China.
Photodiagnosis Photodyn Ther. 2022 Mar;37:102709. doi: 10.1016/j.pdpdt.2021.102709. Epub 2021 Dec 30.
Actinic keratosis(AK) is a common premalignant skin lesion that can progress to invasive squamous cell carcinoma(iSCC). Clinically, AK presents as reddish or brownish macules, papules, or hyperkeratotic plaques. AK cannot be reliably predicted whether it will transform into invasive carcinomas, so skin biopsy is currently a gold standard for identifying suspicious malignancy. Currently, there are non-invasive methods to help diagnose and determine the difference between AKs and iSCC. For example, dermoscopy and ultrasound can be very useful in diagnosing and monitoring skin diseases non-invasively. Therefore, we report a case of multiple facial AKs with poorly differentiated skin squamous cell carcinoma, which was diagnosed early through dermoscopy and ultrasound, and confirmed by histopathology.
光化性角化病（AK）是一种常见的癌前皮肤病变，可进展为侵袭性鳞状细胞癌（iSCC）。临床上，AK 表现为红色或棕色的斑片、丘疹或角化过度斑块。AK 不能可靠地预测是否会转化为侵袭性癌，因此皮肤活检目前是识别可疑恶性肿瘤的金标准。目前，有一些非侵入性的方法可以帮助诊断并区分 AK 和 iSCC。例如，皮肤镜和超声检查在无创诊断和监测皮肤疾病方面非常有用。因此，我们报告了一例多发性面部 AK 伴分化不良的皮肤鳞状细胞癌，通过皮肤镜和超声检查早期诊断，并通过组织病理学证实。
