Department of Pharmacy, Radboud Institute for Health Sciences, Radboud University Medical Centre, P.O. Box 9101, 6500, HB, Nijmegen, the Netherlands.
Department of Clinical Pharmacy, Division of Laboratory, Pharmacy and Genetics, University Medical Centre Utrecht, P.O. Box 85500, 3508, GA, Utrecht, the Netherlands; Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences (UIPS), Faculty of Science, Utrecht University, P.O. Box 80082, 3508, TB, Utrecht, the Netherlands.
Res Social Adm Pharm. 2022 Aug;18(8):3329-3337. doi: 10.1016/j.sapharm.2021.12.004. Epub 2021 Dec 25.
Redispensing medication unused by patients to other patients could reduce the environmental burden of medication waste. Simultaneously, associated financial loss could be reduced, particularly for expensive medication such as oral anticancer drugs. An important determinant for successful medication redispensing is patient participation.
OBJECTIVE(S): To identify key factors underlying the willingness of patients with cancer to participate in the redispensing of unused oral anticancer drugs.
Semi-structured interviews via telephone or video call were conducted with adult patients diagnosed with cancer from two Dutch hospitals. The interview guide was framed using the COM-B model for behavioural change, to elicit patients' capability, opportunity and motivation to participate in medication redispensing. Questions were related to patients' willingness to accept redispensed medication, reasons thereof, perceived concerns and needs. Inductive thematic analysis was applied.
Seventeen patients (aged 38-82 years, 71% female), with nine different types of cancer participated. The majority of participants supported medication redispensing. Four categories of key factors underlying the willingness of patients with cancer to participate in medication redispensing were identified. First, the driver for participation was having positive societal impact, relating to affordability and sustainability of healthcare. Second, having trust in product quality was a requirement, influenced by preconceived beliefs, quality assurance and patients' knowledge of this process. Third, a facilitator for participating in medication redispensing was adequate provision of information. This concerned awareness of medication waste, information about medication redispensing, support from healthcare providers and other patients, and insight into medication dispensing history. Last, a convenient process for returning unused medication to pharmacies would facilitate participation in medication redispensing.
The willingness of patients with cancer to participate in medication redispensing relates to a drive for achieving positive societal impact, provided that medication is of high quality, there is adequate information provision and a convenient process.
将患者未使用的药物重新分发给其他患者可以减少药物浪费对环境的影响。同时,可以减少相关的经济损失,特别是对于昂贵的药物,如口服抗癌药物。成功进行药物再分配的一个重要决定因素是患者的参与。
确定癌症患者参与未使用的口服抗癌药物再分配的意愿的关键因素。
通过电话或视频通话对来自荷兰两家医院的成年癌症患者进行了半结构化访谈。访谈指南是使用行为改变的 COM-B 模型构建的,以引出患者参与药物再分配的能力、机会和动机。问题涉及患者接受再分配药物的意愿、原因、感知到的顾虑和需求。采用归纳主题分析。
17 名患者(年龄 38-82 岁,71%为女性)参与了 9 种不同类型的癌症。大多数参与者支持药物再分配。确定了癌症患者愿意参与药物再分配的四个关键因素类别。首先,参与的驱动力是对社会产生积极影响,与医疗保健的可负担性和可持续性有关。其次,对产品质量的信任是必要的,这受到预先存在的信念、质量保证以及患者对这一过程的了解的影响。第三,参与药物再分配的促进因素是充分提供信息。这涉及对药物浪费的认识、药物再分配信息、来自医疗保健提供者和其他患者的支持,以及对药物配药历史的了解。最后,方便将未使用的药物返还给药店的过程将促进药物再分配的参与。
癌症患者愿意参与药物再分配,这与实现积极的社会影响的动力有关,前提是药物质量高,信息充分,过程方便。