Department of Orthopedics and Sports Medicine, The First Affiliated Hospital of Soochow University, Suzhou, PR China; Suzhou Medical College of Soochow University, Suzhou, PR China.
Department of Orthopedics and Sports Medicine, The First Affiliated Hospital of Soochow University, Suzhou, PR China.
Eur J Radiol. 2022 Feb;147:110130. doi: 10.1016/j.ejrad.2021.110130. Epub 2021 Dec 27.
We conducted a prospective magnetic resonance imaging(MRI) surveillance program of the whole spine twice a day to aim at investigating the diurnal prevalence of MRI parameters of intervertebral discs and their associations with relevant symptoms.
Sixty-four young volunteers underwent MRI of the whole spine twice on the same day (in the morning and evening). Sagittal T2-weighted MRIs of the whole spine were compared and analyzed. Two independent observers assessed the images for the disc height, anterior-posterior distance, and T2 values. Subject demographics and clinical findings were assessed by standardized questionnaires.
There was a statistically significant diurnal disc height change in all the disc level groups. Except four lumbar levels, there was no statistically significant diurnal disc AP distance change seen in other levels. There were statistically significant diurnal T2 value changes in all intervertebral discs except T3/4 levels. The multivariate linear regression analysis showed a positive linear trend association between BMI and the diurnal variations of T1/2 T2 value, T12/L1, L1/2, L2/3, L3/4,L4/5 and L5/S1 disc heights (p < 0.05) . Smoking and passive smoking affected cervical levels of T2 value changes. Interestingly, a reverse trend was observed in all disc changes in the case of more than ten years shift work history.
Smoking and passive smoking are associated with cervical disc T2 value diurnal changes and BMI is associated with lumbar disc height changes. Long time disruption of circadian clock may cause reverse changes of discs, however not in short or medium-time shift workers.
我们进行了一项前瞻性的磁共振成像（MRI）脊柱全面监测计划，每天两次，旨在研究椎间盘 MRI 参数的昼夜变化及其与相关症状的关系。
64 名年轻志愿者在同一天进行了两次脊柱全面 MRI（上午和晚上）。比较和分析整个脊柱矢状 T2 加权 MRI。两名独立观察者评估椎间盘高度、前后距离和 T2 值的图像。通过标准化问卷评估受试者的人口统计学和临床发现。
所有椎间盘水平组均存在统计学上显著的椎间盘高度昼夜变化。除了四个腰椎水平外，其他水平均未见统计学上显著的椎间盘前后距离昼夜变化。除了 T3/4 水平外，所有椎间盘均存在统计学上显著的昼夜 T2 值变化。多元线性回归分析显示，BMI 与 T1/2 T2 值、T12/L1、L1/2、L2/3、L3/4、L4/5 和 L5/S1 椎间盘高度的昼夜变化呈正线性趋势相关（p<0.05）。吸烟和被动吸烟会影响颈椎 T2 值变化。有趣的是，在超过十年轮班工作史的情况下，所有椎间盘变化都出现了相反的趋势。
吸烟和被动吸烟与颈椎间盘 T2 值的昼夜变化有关，BMI 与腰椎间盘高度变化有关。昼夜节律时钟的长时间破坏可能导致椎间盘发生反向变化，但在短时间或中时间轮班工作者中不会发生。
