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一位曾患有脑桥卒中的患者新发眼球震颤。

New-onset Oscillopsia in a Patient With a History of Pontine Stroke.

机构信息

Faculty of Medicine (AK), University of Toronto, Toronto, Canada; Faculty of Medicine (LD, EM), Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada; and Faculty of Medicine (EM), Division of Neurology, Department of Medicine, University of Toronto, Toronto, Canada .

出版信息

J Neuroophthalmol. 2022 Jun 1;42(2):e520-e522. doi: 10.1097/WNO.0000000000001461. Epub 2021 Dec 28.

DOI:10.1097/WNO.0000000000001461
PMID:34974486
Abstract

A 69-year-old man with a history of pontine hemorrhage 2 years ago noticed binocular vertical diplopia after the stroke. On examination, there was a small-angle incomitant left hyperdeviation that did not fit the 3-step test for fourth nerve palsy and incyclotorsion of the higher eye. On motility testing, there was an obvious pendular nystagmus. Resting tremor of the right hand was noticed on neurological examination. Examination of the oropharynx revealed rhythmic oscillations of the soft palate synchronous with the eye oscillations and hand tremor. These findings established a diagnosis of oculopalatal myoclonus (OPM). Although OPM is a well-described entity, this case is unique because the patient was completely asymptomatic from OPM and did not complain of oscillopsia but was very bothered by vertical diplopia because of skew deviation. It also demonstrates that OPM may coexist with skew deviation because anatomically vestibulo-ocular pathway is close to the triangle of Guillain-Mollaret and patients with lesions in one pathway should be examined for abnormalities in the other. Finally, it reminds us about the importance of monitoring patients with a history of brainstem insults for emergence of synchronous tremors years later and that simple maneuver-like ex/amining oropharynx may provide a clear diagnosis.

摘要

一位 69 岁的男性,2 年前有桥脑出血病史,中风后出现双眼垂直复视。检查发现左眼小角度伴视不能,不符合第四对颅神经麻痹的 3 步测试和高眼的内旋扭转。在运动测试中,存在明显的摆动性眼球震颤。神经检查时发现右手有静止性震颤。检查口咽部时发现软腭与眼球震颤和手部震颤同步出现有节律性的摆动。这些发现确立了眼-腭肌阵挛(OPM)的诊断。虽然 OPM 是一种描述明确的病症,但本例是独特的,因为患者完全无症状,没有抱怨眼球震颤,但因斜视角而非常困扰垂直复视。它还表明 OPM 可能与斜视角共存,因为解剖上前庭眼通路靠近 Guillain-Mollaret 三角,因此一条通路的病变患者应检查另一条通路是否有异常。最后,它提醒我们,对于有脑干损伤病史的患者,多年后出现同步震颤的情况,应进行监测,而且简单的口咽部检查可能会提供明确的诊断。

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