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贲门失弛缓症患者行 Heller 心肌切开术+DOR 胃底折叠术与内镜球囊扩张术治疗的症状缓解效果比较:一项三级保健医院的研究。

Resolution of symptoms after Heller's cardiomyotomy with DOR fundoplication versus endoscopic balloon dilatation in patients with achalasia Cardia at tertiary care hospital.

机构信息

Department of Surgery, Dow University of Health Sciences, Civil Hospital, Karachi.

Department of Surgery, Dow University of Health Sciences, Civil Hospital, Karachi, Pakistan.

出版信息

J Pak Med Assoc. 2021 Oct;71(10):2321-2324. doi: 10.47391/JPMA.11-1350.

Abstract

OBJECTIVE

To compare improvement in symptoms following Heller's myotomy with Dor fundoplication and endoscopic pneumatic dilatation for the treatment of achalasia cardia.

METHODS

The prospective comparative study was conducted at the Department of Upper Gastroenterology and Minimally Invasive Surgery, Civil Hospital, Karachi, from February 2016 to January 2019, and comprised patients diagnosed with achalasia cardia on oesophageal manometry. The subjects were randomised into endoscopic pneumatic dilatation group A and laparoscopic Heller's myotomy with Dor fundoplication group B. Eckardt scores were compared between the groups at one-year follow-up. Data was analysed using SPSS 22.

RESULTS

Of the 42 patients, 21(50%) were in each of the two groups. The mean age of patients in group A was 37±12.87 years compared to 34±8.59 years in group B. Treatment success in group A was 11(52%) compared to 21(76%) in group B. Eckardt scores between the groups were significant (p<0.001). Patient satisfaction was significantly more in group B (p<0.05).

CONCLUSIONS

The efficacy of Heller's myotomy with Dor fundoplication was found to be greater than endoscopic pneumatic dilatation for improvement in dysphagia and overall patient satisfaction at one-year follow-up.

摘要

目的

比较 Heller 肌切开术联合 Dor 胃底折叠术与内镜下气囊扩张术治疗贲门失弛缓症的症状改善情况。

方法

本前瞻性对照研究于 2016 年 2 月至 2019 年 1 月在卡拉奇市民事医院上消化道科和微创外科进行,纳入经食管测压诊断为贲门失弛缓症的患者。将患者随机分为内镜下气囊扩张组(A 组)和腹腔镜 Heller 肌切开术联合 Dor 胃底折叠术组(B 组)。在一年随访时比较两组的 Eckardt 评分。使用 SPSS 22 进行数据分析。

结果

42 例患者中,每组 21 例(50%)。A 组患者的平均年龄为 37±12.87 岁,B 组为 34±8.59 岁。A 组治疗成功率为 11(52%),B 组为 21(76%)。两组的 Eckardt 评分差异有统计学意义(p<0.001)。B 组患者的满意度明显更高(p<0.05)。

结论

与内镜下气囊扩张术相比,Heller 肌切开术联合 Dor 胃底折叠术在改善吞咽困难和提高整体患者满意度方面的疗效在一年随访时更为显著。

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