Mašić Silvija, Pezelj Ivan, Krušlin Božo
1Ljudevit Jurak Department of Pathology and Cytology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 2Department of Urology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia; 3Department of Pathology, School of Medicine, University of Zagreb, Zagreb, Croatia.
Acta Clin Croat. 2019 Nov;58(Suppl 2):12-15. doi: 10.20471/acc.2019.58.s2.02.
Prostatic adenocarcinoma (PC) comprises around 19% of malignancies in Croatian male population. On the basis of PSA value, Gleason score, grading group and clinical stage, PC can be classified into low- and high-risk groups which is significant for different therapeutic regimens and prognostic outcomes. In this retrospective study, we analyzed the difference in preoperative PSA value in a group of 272 patients who underwent radical prostatectomy and were diagnosed with PC adenocarcinoma in our institution in a period from January 1, 2018 untill December 31, 2018. Subsequently, they were divided into low- and high-risk prostatic adenocarcinoma groups. Our results demonstrated positive correlation in preoperative PSA values between the groups and therefore support the use of PSA as one of the parameters in defining low- and high-risk prostatic adenocarcinoma categories.
前列腺腺癌(PC)约占克罗地亚男性人群恶性肿瘤的19%。根据前列腺特异性抗原(PSA)值、 Gleason评分、分级组和临床分期,PC可分为低风险和高风险组,这对于不同的治疗方案和预后结果具有重要意义。在这项回顾性研究中,我们分析了2018年1月1日至2018年12月31日期间在我们机构接受根治性前列腺切除术并被诊断为PC腺癌的272例患者术前PSA值的差异。随后,他们被分为低风险和高风险前列腺腺癌组。我们的结果表明,两组之间术前PSA值呈正相关,因此支持将PSA用作定义低风险和高风险前列腺腺癌类别的参数之一。